Abstract
The 2-(5-amino-1-phenyl or benzyl)-4-(cyanoformimidoyl)-1H-imidazoles proved to be important intermediates not only in the preparation of new 6-carbamoyl purines but also in the synthesis of 6-amino-purine, 6-cyano-purine and 1,2-dihydropurines. 6-Carbamoyl-2-alkyl-9-(phenyl or benzyl)-9H-purines have been synthesized in high yields by reactions between 2-(5-amino-1-phenyl or benzyl)-4-(cyanoformimidoyl)-1H-imidazoles and acetylacetone at room temperature. Intramolecular hydrogen bonding appears between H of NH2 and N1 at purine ring. All the compounds have been fully characterized by spectroscopic data.
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We are thankful to the Guilan University Research Council for partial support of this work.
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Yahyazadeh, A. (2014). Synthesis and Characterization of 6-Carbamoyl-2-Alkyl-9-(Phenyl or Benzyl)-9H-Purines. In: Gupta Bhowon, M., Jhaumeer-Laulloo, S., Li Kam Wah, H., Ramasami, P. (eds) Chemistry: The Key to our Sustainable Future. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7389-9_10
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