Incidence of Recraniotomy for Postoperative Infections After Surgery for Intracranial Tumors
The prevalence rate for all primary brain and central nervous system tumors is estimated to be 130.8 per 100,000 inhabitants (CTBRUS (2008) Statistical report: primary brain tumors in the United States, 2000–2004. http://www.cbtrus.org/reports//2007-2008/2007report.pdf). The cornerstone of brain tumor treatment is surgery, where the objective is radical surgery within safe limits and to establish an exact tissue diagnosis. However, craniotomies are not without inherent risks, be it surgical mortality, postoperative hematomas or infections. Infections after neurosurgical procedures often present as meningitis, subdural empyema, or cerebral abscess. Although meningitis can often be treated with intravenous antibiotics, cases that involve a bone flap infection, subdural empyema, or cerebral abscess usually require a repeated operation. In a recent large series, 1.5 % of the patients were reoperated for postoperative infection. Of these infections, 59.0 % were extradural. Independent risk factors were male sex and meningioma histopathology. The vast majority of reoperations occurred within 3 months of tumor surgery. The consequences of postoperative infections were generally minor, as 85 % had a good outcome with no or only a mild disability, but within the group of patients reoperated for infection, the mortality rate was 5 %.
KeywordsPostoperative Infection Central Nervous System Tumor Tumor Surgery Bone Flap Maximum Daily Dose
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