Novalis Spinal Radiosurgery

  • David Ly
  • Christopher J. Anker
  • Meic H. Schmidt
Part of the Tumors of the Central Nervous System book series (TCNS, volume 11)


Stereotactic radiosurgery (SRS) is a noninvasive approach to delivering high doses of conformal radiation. The majority of spinal tumors are metastatic lesions, and it is estimated that 30–90 % of cancer patients will develop metastatic spinal lesions. The potential benefit of spinal SRS may arise in cases of reirradiation where conformal dose distribution and a noninvasive approach are desired. Current techniques require a high degree of precision with patient simulation. Retrospective studies have favored a spinal SRS fractionation schema of ≥14 Gy in one fraction in previously unirradiated patients, with the majority of 1-year local and pain control estimates above 80 %. Radiation-induced myelopathy from spinal SRS is exceedingly rare, but may occur 6–12 months after treatment. Follow-up after spinal SRS is important since intervention after radiation-induced myelopathy may alleviate neurologic symptoms. Randomized clinical trials are examining the feasibility and ability of spinal SRS to deliver improved outcomes for pain relief compared with conventional three-dimensional conformal external beam radiotherapy.


Spinal Cord Compression Stereotactic Body Radiation Therapy Spinal Metastasis Spinal Lesion Biologic Equivalent Dose 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • David Ly
    • 1
  • Christopher J. Anker
    • 1
  • Meic H. Schmidt
    • 2
  1. 1.Department of Radiation Oncology, Huntsman Cancer HospitalUniversity of UtahSalt Lake CityUSA
  2. 2.Department of Neurosurgery, Huntsman Cancer InstituteUniversity of UtahSalt Lake CityUSA

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