Abstract
Endoscopic retrograde cholangiopancreatography (ERCP) with stenting has been used in the palliation of malignant obstructive jaundice for nearly three decades [1-3]. The initial success of endoscopic internal biliary drainage [1, 2], coupled with its low invasiveness [4] as a form of palliation, led to the suggestion that it represented the treatment of choice for unresectable cholangiocarcinomas [2] over the percutaneous or surgical alternatives. Endoscopic stenting of malignant hilar strictures, however, remains a technically challenging prospect. This, along with advances in interventional radiology over the years amongst other reasons, has precluded the development of clear delineation of the ideal technique for palliating hilar cholangiocarcinomas. In most instances, the extent of the obstruction, the anatomical arrangement of the intrahepatic ducts and the available local expertise shall determine the approach.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Cotton PB. Endoscopic methods for relief of malignant obstructive jaundice. World J Surg. 1984;8(6):854–61.
Deviere J, Baize M, de Toeuf J, et al. Long-term follow-up of patients with hilar malignant stricture treated by endoscopic internal biliary drainage. Gastrointest Endosc. 1988;34(2):95–101.
Soehendra N, Reynders-Frederix V. Palliative bile duct drainage—a new endoscopic method of introducing a transpapillary drain. Endoscopy. 1980;12(1):8–11.
Speer AG, Cotton PB, Russell RC, et al. Randomised trial of endoscopic versus percutaneous stent insertion in malignant obstructive jaundice. Lancet. 1987;2(8550):57–62.
Schmassmann A, von Gunten E, Knuchel J, et al. Wallstents versus plastic stents in malignant biliary obstruction: effects of stent patency of the first and second stent on patient compliance and survival. Am J Gastroenterol. 1996;91(4):654–9.
Wilson M. The application of metallic stents in malignant biliary obstruction. Tech Vasc Interv Radiol. 1999;2(1):39–52.
Moss AC, Morris E, Leyden J, et al. Do the benefits of metal stents justify the costs? A systematic review and meta-analysis of trials comparing endoscopic stents for malignant biliary obstruction. Eur J Gastroenterol Hepatol. 2007;19(12):1119–24.
Cipolletta L, Rotondano G, Marmo R, et al. Endoscopic palliation of malignant obstructive jaundice: an evidence-based review. Dig Liver Dis. 2007;39(4):375–88.
Cheng JL, Bruno MJ, Bergman JJ, et al. Endoscopic palliation of patients with biliary obstruction caused by nonresectable hilar cholangiocarcinoma: efficacy of self-expandable metallic Wallstents. Gastrointest Endosc. 2002;56(1):33–9.
De Palma GD, Pezzullo A, Rega M, et al. Unilateral placement of metallic stents for malignant hilar obstruction: a prospective study. Gastrointest Endosc. 2003;58(1):50–3.
Liu CL, Lo CM, Lai EC, et al. Endoscopic retrograde cholangiopancreatography and endoscopic endoprosthesis insertion in patients with Klatskin tumors. Arch Surg. 1998;133(3):293–6.
Peters RA, Williams SG, Lombard M, et al. The management of high-grade hilar strictures by endoscopic insertion of self-expanding metal endoprostheses. Endoscopy. 1997;29(1):10–6.
Lee SH, Park JK, Yoon WJ, et al. Optimal biliary drainage for Âinoperable Klatskin’s tumor based on Bismuth type. World J Gastroenterol. 2007;13(29):3948–55.
Paik WH, Park YS, Hwang JH, et al. Palliative treatment with self-expandable metallic stents in patients with advanced type III or IV hilar cholangiocarcinoma: a percutaneous versus endoscopic approach. Gastrointest Endosc. 2009;69(1):55–62.
Pinol V, Castells A, Bordas JM, et al. Percutaneous self-expanding metal stents versus endoscopic polyethylene endoprostheses for treating malignant biliary obstruction: randomised clinical trial. Radiology. 2002;225(1):27–34.
Moorthy S, Prabhu N, Sreekumar K, et al. Hilar cholangiocarcinoma: results of percutaneous stenting with self-expandable metal stents. Indian J Radiol Imaging. 2004;14:45–51.
Neal CP, Thomasset SC, Bools D, et al. Combined percutaneous-endoscopic stenting of malignant biliary obstruction: results from 106 consecutive procedures and identification of factors associated with adverse outcome. Surg Endosc. 2010;24(2):423–31.
Dowsett JF, Vaira D, Hatfield AR, et al. Endoscopic biliary therapy using the combined percutaneous and endoscopic technique. Gastroenterology. 1989;96(4):1180–6.
De Palma GD, Galloro G, Siciliano S, et al. Unilateral versus bilateral endoscopic hepatic duct drainage in patients with malignant hilar biliary obstruction: results of a prospective, randomised, and controlled study. Gastrointest Endosc. 2001;53(6):547–53.
Polydorou AA, Chisholm EM, Romanos AA, et al. A comparison of right versus left hepatic duct endoprosthesis insertion in malignant hilar biliary obstruction. Endoscopy. 1989;21(6):266–71.
Chang WH, Kortan P, Haber GB. Outcome in patients with bifurcation tumors who undergo unilateral versus bilateral hepatic duct drainage. Gastrointest Endosc. 1998;47(5):354–62.
Dumas R, Demuth N, Buckley M, et al. Endoscopic bilateral metal stent placement for malignant hilar stenoses: identification of optimal technique. Gastrointest Endosc. 2000;51(3):334–8.
Naitoh I, Ohara H, Nakazawa T, et al. Unilateral versus bilateral endoscopic metal stenting for malignant hilar biliary obstruction. J Gastroenterol Hepatol. 2009;24(4):552–7.
Lee JH, Kang DH, Kim JY, et al. Endoscopic bilateral metal stent placement for advanced hilar cholangiocarcinoma: a pilot study of a newly designed Y stent. Gastrointest Endosc. 2007;66(2):364–9.
Kim JY, Kang DH, Kim HW, et al. Usefulness of slimmer and open-cell-design stents for endoscopic bilateral stenting and endoscopic revision in patients with hilar cholangiocarcinoma (with video). Gastrointest Endosc. 2009;70(6):1109–15.
Kim JY, Kang DH, Choi CW, et al. Selective intrahepatic duct cannulation by using a triple-lumen catheter for endoscopic bilateral stenting in hilar cholangiocarcinoma. Gastrointest Endosc. 2010;72(1):192–8.
Wagner HJ, Knyrim K, Vakil N, et al. Plastic endoprostheses versus metal stents in the palliative treatment of malignant hilar biliary obstruction. A prospective and randomised trial. Endoscopy. 1993;25(3):213–8.
Kaassis M, Boyer J, Dumas R, et al. Plastic or metal stents for malignant stricture of the common bile duct? Results of a randomised prospective study. Gastrointest Endosc. 2003;57(2):178–82.
Ortner ME, Caca K, Berr F, et al. Successful photodynamic therapy for nonresectable cholangiocarcinoma: a randomised prospective study. Gastroenterology. 2003;125(5):1355–63.
Zoepf T, Jakobs R, Arnold JC, et al. Palliation of nonresectable bile duct cancer: improved survival after photodynamic therapy. Am J Gastroenterol. 2005;100(11):2426–30.
Cheung KL, Lai EC. Endoscopic stenting for malignant biliary obstruction. Arch Surg. 1995;130(2):204–7.
Ballinger AB, McHugh M, Catnach SM, et al. Symptom relief and quality of life after stenting for malignant bile duct obstruction. Gut. 1994;35(4):467–70.
Luman W, Cull A, Palmer KR. Quality of life in patients stented for malignant biliary obstructions. Eur J Gastroenterol Hepatol. 1997;9(5):481–4.
Siegel JH, Snady H. The significance of endoscopically placed prostheses in the management of biliary obstruction due to carcinoma of the pancreas: results of nonoperative decompression in 277 patients. Am J Gastroenterol. 1986;81(8):634–41.
Pisello F, Geraci G, Modica G, et al. Cholangitis prevention in endoscopic Klatskin tumor palliation: air cholangiography technique. Langenbecks Arch Surg. 2009;394(6):1109–14.
Singh V, Singh G, Gupta V, et al. Contrast-free air cholangiography-assisted unilateral plastic stenting in malignant hilar biliary obstruction. Hepatobiliary Pancreat Dis Int. 2010;9(1):88–92.
Will U, Thieme A, Fueldner F, et al. Treatment of biliary obstruction in selected patients by endoscopic ultrasonography (EUS)-guided transluminal biliary drainage. Endoscopy. 2007;39(4):292–5.
Yamao K, Bhatia V, Mizuno N, et al. EUS-guided choledochoduodenostomy for palliative biliary drainage in patients with malignant biliary obstruction: results of long-term follow-up. Endoscopy. 2008;40(4):340–2.
Geller A. Klatskin tumor–palliative therapy: the jury is still out or may be not yet in. Gastrointest Endosc. 2009;69(1):63–5.
Hausegger KA, Kleinert R, Lammer J, et al. Malignant biliary obstruction: histologic findings after treatment with self-expandable stents. Radiology. 1992;185(2):461–4.
Mueller PR, Ferrucci Jr JT, Teplick SK, et al. Biliary stent endoprosthesis: analysis of complications in 113 patients. Radiology. 1985;156(3):637–9.
Acknowledgements
The authors wish to acknowledge the help of Dr. Christopher Worthley who provided the ERCP images.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer Science+Business Media Dordrecht and People's Medical Publishing House
About this chapter
Cite this chapter
Toouli, J., Barreto, S.G. (2013). Palliation by Endoscopic Approach. In: Lau, W. (eds) Hilar Cholangiocarcinoma. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6473-6_28
Download citation
DOI: https://doi.org/10.1007/978-94-007-6473-6_28
Published:
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-007-6472-9
Online ISBN: 978-94-007-6473-6
eBook Packages: MedicineMedicine (R0)