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Radiation Proteomics pp 37–48Cite as

Ionizing Radiation Effects on Cells, Organelles and Tissues on Proteome Level

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 990))

Abstract

This chapter will review the proteome alterations induced by ionizing radiation in cellular systems or using animal models with whole body or localised exposure. The recent developments in qualitative and quantitative proteome analysis using formalin-fixed paraffin-embedded material from radiobiology archives will be illustrated. The development of promising protein targets to be used as radiation biomarkers in future molecular epidemiology studies is described.

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Authors and Affiliations

  1. Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Radiation Biology, Ingolstädter Landstrasse 1, Neuherberg, 85764, Germany

    Soile Tapio

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  1. Radiation and Nuclear Safety Authority, STUK, Laippatie 4, Helsinki, 00880, Finland

    Dariusz Leszczynski

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Tapio, S. (2013). Ionizing Radiation Effects on Cells, Organelles and Tissues on Proteome Level. In: Leszczynski, D. (eds) Radiation Proteomics. Advances in Experimental Medicine and Biology, vol 990. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5896-4_2

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