Polypharmacy and Potentially Inappropriate Medication Use Among Elders with Dementia

  • Jan Luzny


Senior patients are at hight risk of polymorbidity which may correspond with hight risk of polypharmacy. Benefit of pharmacotherapy on one hand and risk of pharmacotherapy on the other hand are two different scales of one balance we have to measure on.

The paper shows basic principles of safe and efficient pharmacotherapy in the elderly – including inappropriate psychotropic drugs and drug-drug interactions which should be avoided.


Geriatric Medicine Geriatric Psychiatry Inappropriate Medication Confusional State Adjustment Disorder 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.





cytochrome P450 superfamily



MAO inhibitors

monoamine oxidase inhibitors


melatonin agonist and selective serotonin antagonist


noradrenergic and specific serotonergic antidepressant


noradrenergic and dopaminergic reuptake inhibitor


nonsteroid anti-inflammatory drugs


QT interval in electrocardiogram


serotonin antagonist reuptake inhibitor


syndrome of inappropriate antidiuretic hormone secretion


serotonin noradrenaline reuptake inhibitors


selective serotonin reuptake inhibitors


tricyclic antidepressants


zolpidem zopiclone, zaleplone



The paper was not supported by any grant or other financial support. Ethical hazard is therefore excluded.


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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  1. 1.Mental Hospital Kromeriz and Palacky University OlomoucPrahaCzech Republic

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