Marine Collagens

  • Hermann Ehrlich
Part of the Biologically-Inspired Systems book series (BISY, volume 4)


There are three main categories of marine collagens: collagens of invertebrate origin (sponges, jellyfish, molluscs), fish collagens, and marine mammal collagens. Marine fish collagens isolated from skin, meat, scales, fins and waste materials are of particular interest from an industrial point of view. Different types of fish collagen-based biomaterials (gels, scaffolds, sponges, films, membranes, composites) and their biomedical application are discussed in this chapter.


Denaturation Temperature Fish Scale Collagen Peptide Ultrasonic Pretreatment Fish Collagen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Abderhalden E, Voitinovic I (1907) Weitere Beiträge zur Kenntnis der Zusammensetzung der Proteine. Hoppe Seylers Z Physiol Chem 52(3–4):368–374CrossRefGoogle Scholar
  2. Allard R, Devictor P, Huc A et al (1995) Unpigmented fish skin, particularly from flat fish, as a novel industrial source of collagen, extraction method, collagen and biomaterial thereby obtained. US Patent 5,420,248Google Scholar
  3. Andre V, Abdul Malak N et al (2000) Use of collagen of aquatic origin for the production of supports for tissue engineering, and supports and biomaterials obtained. US Patent 6,541,023Google Scholar
  4. Bairati A, Garrone R (1985) Biology of invertebrate and lower vertebrate collagens. Plenum, New YorkCrossRefGoogle Scholar
  5. Benjakul S, Nalinanon S, Shahidi F (2012) Fish collagen. In: Simpson BK (ed) Food biochemistry and food processing, 2nd edn. Wiley-Blackwell, Oxford. Copyright © 2012 John Wiley & Sons, Inc. Reproduced with permissionGoogle Scholar
  6. Beveridge JMR, Lucas CC (1944) Amino acids of isinglass. J Biol Chem 155:547–556Google Scholar
  7. Bigi A, Burghammer M, Falconi R et al (2001) Twisted plywood pattern of collagen fibrils in teleost scales: an X–ray diffraction investigation. J Struct Biol 136:137–143CrossRefGoogle Scholar
  8. Burdak VD (1979) Morphologie fonctionnelle du tégument écailleux des poissons. La Pensée Scientifique, Kiev (en russe). traduction française in Cybium (Paris), 1986, 10 (3) supplément:147 pGoogle Scholar
  9. Burley RW, Solomons CC (1955) The action of fluorodinitrobenzene on ichthylepidin. Acta Bioenerg 18(1):137–138Google Scholar
  10. Castillo–Briceño P, Sepulcre MP, Chaves–Pozo E et al (2009) Collagen regulates the activation of professional phagocytes of the teleost fish gilthead seabream. Mol Immunol 46:1409–1415CrossRefGoogle Scholar
  11. Castillo-Briceño P, Bihan D, Nilges M et al (2011) A role for specific collagen motifs during wound healing and inflammatory response of fibroblasts in the teleost fish gilthead seabream. Mol Immunol 48(6–7):826–834. © 2010 Elsevier Ltd. All rights reserved. (Published under a Creative Commons license)CrossRefGoogle Scholar
  12. Chen L, Bao B, Wang N et al (2012) Oral administration of shark type II collagen suppresses complete Freund’s adjuvant-induced rheumatoid arthritis in rats. Pharmaceuticals (Basel) 5(4):339–352. © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (
  13. Ciarlo AS, Paredi ME, Fraga AN (1997) Isolation of soluble collagen from hake skin (Merluccius hubbsi). J Aqua Food Prod Technol 6:65–77CrossRefGoogle Scholar
  14. Darby A (2010) Australian firm sells sperm whale extract. Published on-line (16.07.2010). Accessed 15 May 2014. Copyright © 2014 Fairfax Media. Reprinted with permission
  15. Davenport J (2005) Swimbladder volume and body density in an armoured benthic fish, the streaked gurnard. J Fish Biol 55:527–534CrossRefGoogle Scholar
  16. Divya PV, Nandakumar K (2006) Local drug delivery – Periocol® in periodontics. Trends Biomater Artif Organs 19:74–80Google Scholar
  17. Eaglstein WH, Alvarez OM, Auletta M et al (1999) Acute excisional wounds treated with a tissue–engineered skin (Apligraf). Dermatol Surg 25:195–201CrossRefGoogle Scholar
  18. Eastoe JE (1957) The amino acid composition of fish collagen and gelatin. Biochem J 65(2):363–368Google Scholar
  19. Ehrlich H (2010) Biological materials of marine origin. Invertebrates. Springer biological materials of marine origin by Ehrlich, Hermann Reproduced with permission of Springer in the format Book via Copyright Clearance CenterGoogle Scholar
  20. Ehrlich H (2012) Collagens of aquatic invertebrates: insights, trends and open questions. In: Proceedings of the 5th Freiberg Collagen Symposium, Freiberg, Germany, 4–5 September 2012Google Scholar
  21. Ehrlich H, Deutzmann R, Brunner E et al (2010) Mineralization of the metre–long biosilica structures of glass sponges is templated on hydroxylated collagen. Nat Chem 2(12):1084–1088CrossRefGoogle Scholar
  22. Engel J (1997) Versatile collagens in invertebrates. Science 277:1785–1786CrossRefGoogle Scholar
  23. Exposito JY, Cluzel C, Garrone R et al (2002) Evolution of collagens. Anat Rec 268(3):302–316CrossRefGoogle Scholar
  24. Fernandes RM, Couto Neto RG, Paschoal CW et al (2008) Reprinted from Fernandes RM, Couto Neto RG, Paschoal CW et al (2008) Collagen films from swim bladders: preparation method and properties. Colloids Surf B Biointerfaces 62(1):17–21. Copyright (2008), with permission from ElsevierGoogle Scholar
  25. Fujii R (1968) Fine structure of the collagenous lamella underlying the epidermis of the goby, Chasmichthys gulosus. Annot Zool Jpn 41:95–106Google Scholar
  26. Garrone R (1978) Phylogenesis of connective tissue. In: Robert L (ed) Morphological aspects and biosynthesis of sponge intercellular matrix. S. Karger, BaselGoogle Scholar
  27. Garrone R (1999) Evolution of metazoan collagens. Prog Mol Subcell Biol 21:119–139CrossRefGoogle Scholar
  28. Gilbert TW, Sellaro TL, Badylak SF (2006) Decellularization of tissues and organs. Biomaterials 27:3675–3683Google Scholar
  29. Green EH, Tower RW (1901) The organic constituents of the scales of fish. Bull US Fish Comm 21:97–102. Copyright © 1901, National Climatic Data Center, Asheville, NC, USA. Reprinted with permissionGoogle Scholar
  30. Green EH, Tower RW (1902) The organic constituents of the scales of fish. Kessinger Publishing LLC, Whitefish, p 12Google Scholar
  31. Gross J, Sokal Z, Rougvie M (1956) Structural and chemical studies of the connective tissue of marine sponges. J Histochem Cytochem 4:227–246CrossRefGoogle Scholar
  32. Guellec DL, Morvan-Dubois G, Sire J-Y (2004) Skin development in bony fish with particular emphasis on collagen deposition in the dermis of the zebrafish (Danio rerio). Int J Dev Biol 48:217–231. Reproduced with permission from The International Journal of Developmental Biology (Int. J. Dev. Biol.) (2004) 48:217–231. © UBC PressCrossRefGoogle Scholar
  33. Gustavson KH (1942) The directing influence of the organization of proteins upon their reactivity. Svensk kem Tidskr 54:74–83Google Scholar
  34. Hayashi Y et al (2012) Reproduced from Hayashi Y, Yamada S, Yanagiguchi K, Koyama Z, Ikeda T (2012) Chitosan and fish collagen as biomaterials for regenerative medicine. Adv Food Nutr Res 65:107–120. Copyright (2012), with permission from ElsevierGoogle Scholar
  35. Hickman et al (2000) Reprinted from Hickman D, Sims TJ, Miles CA et al (2000) Isinglass/collagen: denaturation and functionality. J Biotechnol 79(3):245–257. Copyright (2000), with permission from ElsevierGoogle Scholar
  36. Higheberger HK (1961) Extraction of collagen. US Patent 2,979,438Google Scholar
  37. Hofman KA, Newberry M (2011) Thermal transition properties of Hoki (Macruronus novaezelandiae) and Ling (Genypterus blacodes) skin collagens: implications for processing. Mar Drugs 9:1176–1186CrossRefGoogle Scholar
  38. Hollister SJ (2009) Scaffold design and manufacturing: from concept to clinic. Adv Mater 21:3330–3342CrossRefGoogle Scholar
  39. Hoyer et al (2012) Reprinted with permission from Hoyer B, Bernhardt A, Heinemann S et al (2012) Biomimetically mineralized salmon collagen scaffolds for application in bone tissue engineering. Biomacromolecules 13(4):1059–1066. Copyright (2012) American Chemical SocietyGoogle Scholar
  40. Hutchinson JJ, Trueman CN (2006) Stable isotope analyses of collagen in fish scales: limitations set by scale architecture. J Fish Biol 69:1874–1880CrossRefGoogle Scholar
  41. Ikoma T, Kobayashi H, Tanaka J et al (2003) Physical properties of type I collagen extracted from fish scales of Pagrus major and Oreochromis niloticas. Int J Biol Macromol 32(3–5):199–204CrossRefGoogle Scholar
  42. Jiang ZN, Bo JQ, Zheng QX et al (2012) Extraction of collagen from fish scales with papain under ultrasonic pretreatment. Adv Mat Res 366:421–424Google Scholar
  43. Jongjareonrak A, Benjakul S, Visessanguan W et al (2005) Isolation and characterisation of acid and pepsin–solubilised collagens from the skin of Brownstripe red snapper (Lutjanus vitta). Food Chem 93:475–484CrossRefGoogle Scholar
  44. Kalyani M (1997) Sugars linked with wish scale protein. Indian J Fish 26:228–229Google Scholar
  45. Kawaguchi (1985) Reproduced from Kawaguchi T (1985) Chemical nature of collagen in the placoid-scale dentine of the blue shark, Prionace glauca L. Arch Oral Biol 30(5):385–390. Copyright (1985), with permission from ElsevierGoogle Scholar
  46. Kawaguchi et al (2011) With kind permission from Springer Science+Business Media: Kawaguchi Y, Kondo E, Kitamura N, Arakaki K, Tanaka Y, Munekata M, Nagai N, Yasuda K (2011) In vivo effects of isolated implantation of salmon-derived crosslinked atelocollagen sponge into an osteochondral defect. J Mater Sci Mater Med 22(2):397–404. Copyright (2011) Springer Science+Business Media, LLCGoogle Scholar
  47. Kawase et al (2010) With kind permission from Springer Science+Business Media: Kawase T, Okuda K, Kogami H et al (2010) Osteogenic activity of human periosteal sheets cultured on salmon collagen-coated ePTFE meshes. J Mater Sci Mater Med 21(2):731–739. Copyright © 2009, Springer Science+Business Media, LLCGoogle Scholar
  48. Kimura S, Ohno Y (1987) Fish type I collagen: tissue–specific existence of two molecular forms, (a1)2a2 and ala2a3, in Alaska Pollack. Comp Biochem Physiol 88B:409–413Google Scholar
  49. Kimura S, Kamimura T, Takema Y et al (1981) Lower vertebrate collagen, evidence for type I–like collagen in the skin of lamprey and shark. Biochim Biophys Acta 669:251–257CrossRefGoogle Scholar
  50. Kimura S, Ohno Y, Miyauchi Y et al (1987) Fish skin type I collagen: wide distribution of an a3 subunit in teleosts. Comp Biochem Physiol B 88:27–34CrossRefGoogle Scholar
  51. Kittiphattanabawon P, Benjakul S, Visessanguan W et al (2005) Characterisation of acid–soluble collagen from skin and bone of bigeye snapper (Priacanthus tayenus). Food Chem 89:363–372CrossRefGoogle Scholar
  52. Kittiphattanabawon P, Benjakul S, Visessanguan W et al (2010) Isolation and characterisation of collagen from the skin of brownbanded bamboo shark (Chiloscyllium punctatum). Food Chem 119:1519–1526CrossRefGoogle Scholar
  53. Lin CC, Ritch R, Lin SM et al (2010) A new fish scale–derived scaffold for corneal regeneration. Eur Cell Mater 19:50–57. Copyright (c) 2010, Lin et al. Reprinted with permissionGoogle Scholar
  54. Ludowieg JJ, Adams J, Wang AC et al (1973) The mammalian intervertebral disc. The collagen of whale fetal nucleus pulposus. Connect Tissue Res 2:21–29CrossRefGoogle Scholar
  55. Matsui R, Ishida M, Kimura S (1991) Characterization of an 3 chain from the skin type I collagen of chum salmon (Oncorhynchus keta). Comp Biochem Physiol B 99:171–174Google Scholar
  56. Meunie FJ (1984) Spatial organization and mineralization of the basal plate of elasmoid scales in osteichthyans. Am Zool 24(4):953–964. By permission of Oxford University PressGoogle Scholar
  57. Meunier FJ (1983) Les tissus osseux des Osteichlhyens. Structure, genese, croissance et evolution. Archives et documents, Micro–edition, Inst Ethnol SN.82–600–328Google Scholar
  58. Mizuta S, Hwang J, Yoshinaka R (2002) Molecular species of collagen from wing muscle of skate (Raja kenojei). Food Chem 76:53–58CrossRefGoogle Scholar
  59. Mori H, Tone Y, Shimizu K, Zikihara K, Tokutomi S, Ida T, Ihara H, Hara M (2013) Studies on fish scale collagen of Pacific saury (Cololabis saira). Mater Sci Eng C 33:174–181. doi: 10.1016/j.msec.2012.08.025 CrossRefGoogle Scholar
  60. Mörner CT (1898) Die organische Grundsubstanz der Fischschuppen vom chemischen Gesichtspunkte aus betrachtet. Zeitschr f Physiol Chemie 24:125–137CrossRefGoogle Scholar
  61. Moura KO, Vieira EFS, Cestari AR (2012) Poly(glutaraldehyde)-stabilized fish scale fibrillar collagen–some features of a new material for heavy metal sorption. J Appl Polym Sci 124:3208–3221. © 2011 Wiley Periodicals, Inc. Reprinted with permissionCrossRefGoogle Scholar
  62. Nadol JB, Gibbons JR, Porter KR (1969) A reinterpretation of the structure and development of the basement lamella: an ordered array of collagen in fish skin. Dev Biol 20:304–331CrossRefGoogle Scholar
  63. Nagai T (2004) Characterization of collagen from Japanese sea bass caudal fin as waste material. Eur Food Res Technol 218:424–427CrossRefGoogle Scholar
  64. Nagai T, Suzuki N (2000) Isolation of collagen from fish waste material – skin, bone and fins. Food Chem 68:277–281CrossRefGoogle Scholar
  65. Nagai T, Araki Y, Suzuki N (2002) Collagen of the skin of ocellate puffer fish (Takifugu rubripes). Food Chem 78:173–177CrossRefGoogle Scholar
  66. Nagai T, Izumi M, Ishii M (2004) Fish scale collagen: preparation and partial characterization. Int J Food Sci Technol 39:239–244CrossRefGoogle Scholar
  67. Nagai N, Mori K, Satoh Y et al (2007) In vitro growth and differentiated activities of human periodontal ligament fibroblasts cultured on salmon collagen gel. J Biomed Mater Res A 82(2):395–402CrossRefGoogle Scholar
  68. Nagai N, Mori K, Munekata M (2008a) Biological properties of crosslinked salmon collagen fibrillar gel as a scaffold for human umbilical vein endothelial cells. J Biomater Appl 23(3):275–287CrossRefGoogle Scholar
  69. Nagai N, Nakayama Y, Zhou YM et al (2008b) Development of salmon collagen vascular graft: mechanical and biological properties and preliminary implantation study. J Biomed Mater Res B Appl Biomater 87B(2):432–439CrossRefGoogle Scholar
  70. Nagai T, Suzuki N, Nagashima T (2008c) Collagen from common minke whale (Balaenoptera acutorostrata) unesu. Food Chem 111:296–301CrossRefGoogle Scholar
  71. Nagai N et al (2009) With kind permission from Springer Science+Business Media: Nagai N, Nakayama Y, Nishi S, Munekata M (2009) Development of novel covered stents using salmon collagen. J Artif Organs 12(1):61–66. Copyright © 2009, The Japanese Society for Artificial OrgansGoogle Scholar
  72. Nalinanon S, Benjakul S, Visessanguan W et al (2007) Use of pepsinfor collagen extraction from the skin of bigeye snapper (Priacanthus tayenus). Food Chem 104:593–601CrossRefGoogle Scholar
  73. Nalinanon S, Benjakul S, Visessanguan W et al (2008) Tuna pepsin: characteristics and its use for collagen extraction from the skin of threadfin bream (Nemipterus spp.). J Food Sci 73:C413–C419CrossRefGoogle Scholar
  74. Nalinanon S, Benjakul S, Kishimura H (2010) Collagens from the skin of arabesque greenling (Pleurogrammus azonus) solubilized with the aid of acetic acid and pepsin from albacore tuna (Thunnus alalunga) stomach. J Sci Food Agric 90(9):1492–1500CrossRefGoogle Scholar
  75. Nomura Y (2004) Properties and utilization of shark collagen. More efficient utilization of fish and fisheries products. Elsevier, New YorkGoogle Scholar
  76. Nomura Y, Yamano M, Shirai K (1995) Renaturation of alpha 1 chains from shark skin collagen type I. J Food Sci 60:1233–1236CrossRefGoogle Scholar
  77. Nomura Y, Yamano M, Hayakawa C et al (1997) Structural property and in vitro self–assembly of shark type I collagen. Biosci Biotechnol Biochem 61:1919–1923CrossRefGoogle Scholar
  78. Nomura Y, Toki S, Ishii Y et al (2000a) The physicochemical property of shark type I collagen gel and membrane. J Agric Food Chem 48:2028–2032CrossRefGoogle Scholar
  79. Nomura Y, Toki S, Ishii Y et al (2000b) Improvement of the material property of shark type I collagen by comparison with pig type I collagen. J Agric Food Chem 48:6332–6633CrossRefGoogle Scholar
  80. Ogawa M, Moody MW, Portier RJ et al (2003) Biochemical properties of black drum and sheepshead seabream skin collagen. J Agric Food Chem 51(27):8088–8892CrossRefGoogle Scholar
  81. Parenteau-Bareil R, Gauvin R, Berthod F (2010) Collagen-based biomaterials for tissue engineering applications. Materials 3(3):1863–1887. © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (
  82. Parravicini R, Cocconcelli F, Verona A et al (2012) Tuna cornea as biomaterial for cardiac applications. Tex Heart Inst J 39(2):179–183Google Scholar
  83. Pati F, Datta P, Adhikari B et al (2012) Collagen scaffolds derived from fresh water fish origin and their biocompatibility. J Biomed Mater Res A 100(4):1068–1079. Copyright © 2012 Wiley Periodicals, IncCrossRefGoogle Scholar
  84. Piez KA, Gross J (1960) The amino acid composition of some fish collagens: the relation between composition and structure. J Biol Chem 235:995–997Google Scholar
  85. Rigby BJ (1968) Amino–acid composition and thermal stability of the skin collagen of the Antarctic ice–fish. Nature 219(5150):166–167CrossRefGoogle Scholar
  86. Rose C, Kumar M, Mandal AB (1988) A study of the hydration and thermodynamics of warm–water and cold–water fish collagens. Biochem J 249:127–133Google Scholar
  87. Sadowska M, Kołodziejska I (2005) Optimisation of conditions for precipitation of collagen from solution using k–carrageenan. Studies on collagen from the skin of Baltic cod (Gadus morhua). Food Chem 91:45–49CrossRefGoogle Scholar
  88. Sadowska M, Kolodziejska I, Niecikowska C (2003) Isolation of collagen from the skin of Baltic cod (Gadus morhua). Food Chem 81:257–262CrossRefGoogle Scholar
  89. Sankar S, Sekar S, Mohan R et al (2008) Preparation and partial characterization of collagen sheet from fish (Lates calcarifer) scales. Int J Biol Macromol 42(1):6–9CrossRefGoogle Scholar
  90. Senaratne et al (2006) Reprinted from Senaratne LS, Park P-J, Kim S-K (2006) Isolation and characterization of collagen from brown backed toadfish (Lagocephalus gloveri) skin. Bioresource Technol 97(2):191–197. Copyright (2006), with permission from ElsevierGoogle Scholar
  91. Seshaiya RV, Ambujabai P, Kalyani M (1963) Amino–acid composition of ichthylepidin of fish scales. JMU 32B:138Google Scholar
  92. Shen X et al (2008) With kind permission from Springer Science+Business Media: Shen X, Nagai N, Murata M et al (2008) Development of salmon milt DNA/salmon collagen composite for wound dressing. J Mater Sci Mater Med 19(12):3473–3479. Copyright © 2008, Springer Science+Business Media, LLCGoogle Scholar
  93. Simpson BK, Benjakul S, Nalinanon S et al (2012) Fish collagen. In: Food biochemistry and food processing, 2nd edn. Wiley. doi: 10.1002/9781118308035.ch20
  94. Singh VP, Nayak DG, Uppoor AS et al (2011) Clinical and radiographic evaluation of nano–crystalline hydroxyapatite bone graft (Sybograf®) in combination with bioresorbable collagen membrane (Periocol®) in periodontal intrabony defects. Dent Res J 9:60–67CrossRefGoogle Scholar
  95. Sire JY (1986) Ontogenic development of surface ornamentation in the scales of Hemichromis bimaculatus (Cichlidae). J Fish Biol 28:713–724CrossRefGoogle Scholar
  96. Skierka E, Sadowska M (2007) The influence of different acid and pepsin on the extractability of collagen from the skin of Baltic cod (Gadus morhua). Food Chem 105:1302–1306CrossRefGoogle Scholar
  97. Sugiura H, Yunoki S, Kondo E et al (2009) In vivo biological responses and bioresorption of tilapia scale collagen as a potential biomaterial. J Biomater Sci Polym Ed 20(10):1353–1368. Copyright © 2009 Taylor & Francis. Reprinted with permissionCrossRefGoogle Scholar
  98. Tabarestani SH, Maghsoudlou Y, Motamedzadegan A et al (2012) Study on some properties of acid–soluble collagens isolated from fish skin and bones of rainbow trout (Onchorhynchus mykiss). Int Food Res J 19(1):251–257Google Scholar
  99. Takahashi T, Yokoyama W (1954) Physico–chemical studies on the skin and leather of marine animals. XII. The content of hydroxyproline in the collagen of different fish skins. Bull Jpn Soc Sci Fish 20:525–529CrossRefGoogle Scholar
  100. Terada M, Izumi K, Ohnuki H et al (2012) Construction and characterization of a tissue-engineered oral mucosa equivalent based on a chitosan-fish scale collagen composite. J Biomed Mater Res 100B:1792–1802. Copyright © 2012 Wiley Periodicals, IncCrossRefGoogle Scholar
  101. Tibbetts IR, Collette BB, Isaac R et al (2007) Functional and phylogenetic implications of the vesicular swimbladder of Hemirhamphus and Oxyporhamphus convexus (Beloniformes: Teleostei). Copeia 4:808–817CrossRefGoogle Scholar
  102. Toshiyuki I, Hisatoshi K, Junzo T (2003) Physical properties of type I collagen extracted from fish scales of Pagrus major and Oreochromis niloticas. Int J Biol Macromol 32:199–204CrossRefGoogle Scholar
  103. Venkatesh S, Dayananda C (2008) Properties, potentials, and prospects of antifreeze proteins. Crit Rev Biotechnol 28:57CrossRefGoogle Scholar
  104. Wang JH, Mizuta S, Yokoyama Y et al (2007a) Purification and characterization of molecular species of collagen in the skin of Skate (Raja kenojei). Food Chem 100:921–925CrossRefGoogle Scholar
  105. Wang L, An X, Xin Z et al (2007b) Isolation and characterization of collagen from the skin of Deep–Sea Redfish (Sebastes mentella). J Food Sci 72:E450–E455CrossRefGoogle Scholar
  106. Wang W, Itoh S, Aizawa T et al (2010) Development of an injectable chitosan/marine collagen composite gel. Biomed Mater 5(6):065009. © IOP Publishing. Reproduced with permission. All rights reservedCrossRefGoogle Scholar
  107. Wittenberg JB, Copeland DE, Haedrich FRL et al (1980) The swimbladder of deep–sea fish: the swimbladder wall is a lipid–rich barrier to oxygen diffusion. J Mar Biol Assoc UK 60:263–276CrossRefGoogle Scholar
  108. Woo JW, Yu SJ, Cho SM et al (2008) Extraction optimization and properties of collagen from yellowfin tuna (Thunnus albacares) dorsal skin. Food Hydrocoll 22:879–887CrossRefGoogle Scholar
  109. Wu CH, Chai HJ (2007) Collagen of fish scale and method of making thereof. United States patent application 20070231878Google Scholar
  110. Xu Z, Ikoma T, Yoshioka T et al (2011) Effect of Glutaraldehyde on properties of membranes prepared from fish scale collagen. MRS proceedings 1418:2012. (doi:  10.1557/opl.2012.396), reproduced with permission. Copyright © 2012, Materials Research Society
  111. Yan M, Li B, Zhao X et al (2008) Characterization of acid–soluble collagen from the skin of walleye pollack (Theragra chalcogramma). Food Chem 107:1581–1586CrossRefGoogle Scholar
  112. Yoshimura K, Terashima M, Hozan D et al (2000) Preparation and dynamic viscoelasticity characterization of alkali–solubilized collagen from shark skin. J Agric Food Chem 48:685–690CrossRefGoogle Scholar
  113. Youn, Shin (2009) Reprinted from Youn HS, Shin TJ (2009) Supramolecular assembly of collagen fibrils into collagen fiber in fish scales of red seabream, Pagrus major. J Struct Biol 168(2):332–336. Copyright (2009), with permission from ElsevierGoogle Scholar
  114. Yunoki S, Suzuki T, Takai M (2003) Stabilization of low denaturation temperature collagen from fish by physical cross–linking methods. J Biosci Bioeng 96:575–577CrossRefGoogle Scholar
  115. Yunoki S, Nagai N, Suzuki T et al (2004) Novel biomaterial from reinforced salmon collagen gel prepared by fibril formation and cross–linking. J Biosci Bioeng 98(1):40–47CrossRefGoogle Scholar
  116. Zelechowska E, Sadowska M, Turk M (2010) Isolation and some properties of collagen from the backbone of Baltic cod (Gadus morhua). Food Hydrocoll 24:325–329CrossRefGoogle Scholar
  117. Zhang F, Wang A, Li Z et al (2011) Preparation and characterisation of collagen from freshwater fish Scales. Food Nutr Sci 2:818–823CrossRefGoogle Scholar
  118. Zylberberg L, Bereiter–Hahn J, Sire JY (1988) Cytoskeletal organization and collagen orientation in the fish scales. Cell Tissue Res 253:597–607CrossRefGoogle Scholar

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© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  • Hermann Ehrlich
    • 1
  1. 1.Institute of Experimental PhysicsTU Bergakademie FreibergFreibergGermany

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