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Tumors of the Central Nervous System, Volume 9 pp 225–230Cite as

Linear Accelerator Radiosurgery for Cavernous Malformation

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Part of the book series: Tumors of the Central Nervous System ((TCNS,volume 9))

Abstract

Cavernous malformation (CM) is a vascular lesion, characterized by low-flow sinusoidal vessels without any intervening neural tissue. The manifestations of CM include headache, seizure, and focal neurological deficits. CMs have been found to be less hazardous than high-flow vascular lesions. The hemorrhage rate is about 0.5–1.6% per patient-year, but the severity of the hemorrhage is usually milder. However, the re-bleeding rate is higher for patients with a history of hemorrhage. Surgical excision is considered to be the most effective treatment to reduce re-bleeding and seizures caused by CMs. However, for deep-seated or multiple lesions, radiosurgery may be considered as an alternative treatment modality because of possible morbidities associated with surgical excision. Although surgical excision also provides the best seizure control, seizures have been occasionally found to occur even after excision. Radiosurgery, including gamma knife and linear accelerator (LINAC), considerably reduces the rates of hemorrhages and seizures; in addition, it is associated with few radiation-induced complications than conventional radiotherapy. In this chapter, we will discuss the feasibility of treating CM by LINAC radiosurgery.

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Authors and Affiliations

  1. Department of Neurosurgery, Chang Gung Memorial Hospital, Linkou, Taiwan

    Yin-Cheng Huang & Peng-Wei Hsu

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  1. Yin-Cheng Huang
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  2. Peng-Wei Hsu
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Correspondence to Peng-Wei Hsu .

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  1. , Kean University, Room 213, Library building, Morris Avenue 1000, Union, 07083, New Jersey, USA

    M.A. Hayat

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Huang, YC., Hsu, PW. (2012). Linear Accelerator Radiosurgery for Cavernous Malformation. In: Hayat, M. (eds) Tumors of the Central Nervous System, Volume 9. Tumors of the Central Nervous System, vol 9. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5488-1_26

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  • DOI: https://doi.org/10.1007/978-94-007-5488-1_26

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  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-007-5487-4

  • Online ISBN: 978-94-007-5488-1

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