Abstract
Neuroblastoma is the most common extracranial solid tumor in children. Adult onset neuroblastoma (ANB) is an extremely rare entity with an incidence of 0.2–0.3 cases per million years. Sites of presentation in adults are similar to children with abdomen and pelvis being the most common; however, some rare sites like thorax and extremities have also been reported in the literature. Unlike the pediatric counterpart it rarely secretes chatecholamines and very few expresses n-myc amplification. Thus the diagnosis relies solely on strong clinicoradiological suspicion along with histopathological and immunohistochemical correlation. The diagnosis of ANB implies an overall poor patient outcome in-spite of indolent course of illness. Unfortunately most of these patients suffer from multiple recurrences even with intensive chemotherapy and myeloablation.
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Singh, M., Agarwal, S., Khurana, N., Kumar, R. (2012). Adult Neuroblastoma Diagnosis. In: Hayat, M. (eds) Tumors of the Central Nervous System, Volume 9. Tumors of the Central Nervous System, vol 9. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5488-1_19
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