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A Coupled Chemomechanical Model for Smooth Muscle Contraction

  • Markus Böl
  • Andre Schmitz

Abstract

This manuscript presents a chemomechanically coupled three-dimensional model, describing the contractile behavior of smooth muscles. It bases on a strain-energy function, additively decomposed into passive parts and an active calcium-driven part related to the chemical contraction of smooth muscle cells. For the description of the calcium phase the four state cross-bridge model of Hai and Murphy (Am. J. Physiol. 254:C99–106, 1988) has been used. Before the features and applicability of the proposed approach are illustrated in terms of three-dimensional boundary-value problems, the model is validated by experiments on porcine smooth muscle tissue strips.

Keywords

Smooth Muscle Contraction Natural Boundary Condition Smooth Muscle Tissue Contraction Process Smooth Muscle Activation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  1. 1.Institute of Solid MechanicsTechnische Universität BraunschweigBraunschweigGermany

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