Abstract
It has been proposed an abstract memory model of cortex that the recurrent network with inhibitory interneurons shows the successive retrieval of memories. It has not, however, been clarified whether such behavior appears in the realistic network model with the Hodgkin-Huxley type of neuron. By using the realistic model that consists of excitatory neurons and inhibitory interneurons, we here show that the successive retrieval of memories is also observed in the network of biologically-plausible model neurons.
Biologically, there is evidence for the involvement of acetylcholine (ACh) in attentional modulation and cholinergic projection decreases IPSPs in pyramidal neurons in layer 2/3 of the cerebral cortex.
Our simulation result shows that the coupling strength of inhibitory interneurons is very crucial for controlling the states of memory retrieval; all firing state, memory completion state and successive memory retrieval state. The field potential of the network in each state of memory retrieval has a specific frequency band. In this paper, we discuss the effects of the coupling strengths of inhibitory interneurons, the states of memory retrieval and the characteristics of frequency band in relation to the neurophysiological experimental data.
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Acknowledgments
This work was supported by a Grant-in-Aid for Scientific Research on Innovative Areas “The study on the neural dynamics for understanding communication in terms of complex hetero systems (No.4103)” (21120002) of The Ministry of Education, Culture, Sports, Science, and Technology, Japan.
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Tsukada, H., Yamaguti, Y., Fujii, H., Tsuda, I. (2013). Transitory Memory Retrieval in the Neural Networks Composed of Pinsky-Rinzel Model Neurons. In: Yamaguchi, Y. (eds) Advances in Cognitive Neurodynamics (III). Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4792-0_91
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DOI: https://doi.org/10.1007/978-94-007-4792-0_91
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