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Quantum Dots for Imaging of Angiogenesis

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The Textbook of Angiogenesis and Lymphangiogenesis: Methods and Applications

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Abstract

Quantum dots (QDs) are inorganic fluorescent nanoparticles that have found tremendous application in the field of biomedical imaging. QDs have superior photoluminescence properties over traditionally utilized fluorescent probes such as being brighter and more photostable. Their unique advantages make them attractive alternatives to conventional fluorescent dyes and show promise in tumor diagnostics and therapy. In recent years, more and more studies show that QD based nanoparticles with specificity for activated endothelial cells can be used to image ongoing angiogenesis. In this chapter, we will briefly introduce the methods of preparing targeted QDs based probes for angiogenesis imaging.

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Authors and Affiliations

  1. Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA

    Ashwinkumar Bhirde, Ruijun Xing, Seulki Lee & Xiaoyuan Chen

Authors
  1. Ashwinkumar Bhirde
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  2. Ruijun Xing
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  3. Seulki Lee
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  4. Xiaoyuan Chen
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Corresponding author

Correspondence to Xiaoyuan Chen .

Editor information

Editors and Affiliations

  1. Radiation Oncology, National Cancer Institute, Angiogenesis Core Facility, Grovemont Circle, Suite 115 8717, Gaithersburg, 20877, Maryland, USA

    Enrique Zudaire

  2. Radiation Oncology, National Cancer Institute, Angiogenesis Core Facility, Grovemont Circle, Suite 115 8717, Gaithersburg, 20877, Maryland, USA

    Frank Cuttitta

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Bhirde, A., Xing, R., Lee, S., Chen, X. (2012). Quantum Dots for Imaging of Angiogenesis. In: Zudaire, E., Cuttitta, F. (eds) The Textbook of Angiogenesis and Lymphangiogenesis: Methods and Applications. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4581-0_20

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