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Teratoid Pediatric Medullomyoblastoma

  • Uygur Er
Chapter
Part of the Pediatric Cancer book series (PECA, volume 3)

Abstract

Cerebellar midline primitive neuroectodermal tumours containing muscle fibers generally referred to as medullomyoblastoma. Medullo­myoblastoma is almost exclusively seen in children. The clinical findings are similar to the every midline posterior fossa tumour. Clinical history is typically brief, the prognosis is very poor. Medullomyoblastomas are seen as solid lesion on computerized tomography and magnetic resonance imaging. They enhance with intravenous contrast media on all imaging sequences. There are four main theories considering histogenesis of the muscle fibers within the tumour. It is accepted as a teratoma or a teratoid tumour widely. Surgical debulking is essential part of the treatment. Postoperative radiotherapy and chemotherapy may be beneficial for lengthening of the survival time. Pathologic examination generally shows two distinct patterns in different areas. Both malignant apparent striated and smooth muscle fibers can be found within the tumour. The documented myogenic differentiation is necessary for the definitive diagnosis.

Keywords

Primitive Neuroectodermal Tumour Obstructive Hydrocephalus Intravenous Contrast Medium Posterior Fossa Tumour Surgical Debulking 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media Dordrecht 2012

Authors and Affiliations

  1. 1.Neurosurgery ClinicTOBB ETU Hospital, The Union of Chambers and Commodity Exchanges of Turkey, Economics and Technology UniversityCankaya, AnkaraTurkey

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