Subcellular Compartmentation of Cysteine Synthesis in Plants – One Step More

  • Malgorzata Lewandowska
  • Frantz Liszewska
  • Markus Wirtz
  • Rüdiger Hell
Conference paper
Part of the Proceedings of the International Plant Sulfur Workshop book series (PIPSW, volume 1)


The cysteine synthase complex (CSC) is supposed to regulate the synthesis of cysteine (Cys). This complex is formed by two enzymes: serine acetyltransferase (SAT) and O-acetyl-serine (thiol) lyase (OAS-TL). The CSC occurs within plant cells in three compartments: cytoplasm, chloroplasts and mitochondria. Cys is one of the substrates for the synthesis of glutathione (GSH) – an important player in regulation of redox-state and stress-response in cells. Here we reported influence of light intensity on transgenic tobacco plants with overexpression of active and inactive forms of Arabidopsis thaliana SAT3 targeted to the cytosol.


Transgenic Tobacco Plant Inactive Form Thiol Level Cysteine Synthesis Small Leaf Area 
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ML was supported by German Academic Exchange Service (DAAD). Support by the German Science foundation (He 1848/13-1) is gratefully acknowledged.


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Copyright information

© Springer Science+Business Media Dordrecht 2012

Authors and Affiliations

  • Malgorzata Lewandowska
    • 1
    • 2
  • Frantz Liszewska
    • 1
  • Markus Wirtz
    • 1
  • Rüdiger Hell
    • 1
  1. 1.Centre for Organismal StudiesUniversity of HeidelbergHeidelbergGermany
  2. 2.Institute for Biochemistry and BiophysicsPolish Academy of SciencesWarsawPoland

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