Arsenic in Rice Grain

  • Andrew A. Meharg
  • Fang-Jie Zhao


To understand the threat posed by arsenic in rice to human food chains, the quantity and chemical species of arsenic ingested by an individual or population have to be assessed, along with gut bioavailability and the hazard associated with that arsenic. This chapter will deal with arsenic present in commercial rice products.


Arsenic Concentration Rice Flour Arsenic Speciation Inorganic Arsenic Total Arsenic 
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  1. Abedin J, Cresser M, Meharg AA, Feldmann J, Cotter-Howells J (2002) Arsenic accumulation and metabolism in rice (Oryza sativa L.). Environ Sci Technol 36:962–968PubMedCrossRefGoogle Scholar
  2. Adomako EE, Williams PN, Deacon C, Meharg AA (2011) Inorganic arsenic and trace element intake from locally produced versus imported rice. Environ Pollut 159:2435–2442PubMedCrossRefGoogle Scholar
  3. Arao T, Maejima Y, Koji B (2009) Uptake of aromatic arsenicals from soil contaminated with diphenylarsinic acid by rice. Environ Sci Technol 43:1097–1101PubMedCrossRefGoogle Scholar
  4. Baba K, Arao T, Maejima Y, Watanabe E, Eun H, Ishizaka M (2008) Arsenic speciation in rice and soil containing related compounds of chemical warfare agents. Anal Chem 80:5768–5775PubMedCrossRefGoogle Scholar
  5. Carey AM, Scheckel KG, Lombi E, Newville M, Choi Y, Norton GJ, Charnock JM, Feldmann J, Price AH, Meharg AA (2010) Grain unloading of arsenic species in rice (Oryza sativa L.). Plant Physiol 150:309–319CrossRefGoogle Scholar
  6. de la Calle MB, Emteborg H, Linsinger TPJ, Montoro R, Sloth JJ, Rubio R, Bacter MJ, Feldmann J, Vermaercke P, Raber G (2011) Does the determination of inorganic arsenic in rice depend on method? Treds Analy Chem 30:641–651CrossRefGoogle Scholar
  7. Duxbury JM, Mayer AB, Lauren JG, Hassan N (2003) Food chain aspects of arsenic contamination in Bangladesh: effects on quality and productivity of rice. J Environ Sci Health A Tox Hazard Subst Environ Eng 38:61–69PubMedCrossRefGoogle Scholar
  8. EFSA (2009) Panel on Contaminants in the Food Chain (CONTAM)/Scientific opinion on arsenic in food. EFSA J 7:1351Google Scholar
  9. Feldmann J, Salaun P, Lombi E (2009) Critical review perspective: elemental speciation analysis methods in environmental chemistry – moving towards methodology. Environ Chem 6:275–289CrossRefGoogle Scholar
  10. Freitas MC, Pacheco AMG, Bacchi MA, Dionisio I, Landsberger S, Fernandes EAN (2008) Compton suppression instrumental neutron activation analysis performance in determining trace- and minor-element contents in foodstuff. J Radioanal Nucl Chem 276:149–156CrossRefGoogle Scholar
  11. Hansen HR, Raab A, Price AH, Duan G, Zhu Y, Norton GJ, Feldmann J, Meharg AA (2011) Identification of tetramethylarsonium in rice grains with elevated arsenic content. J Environ Monit 13:32–34PubMedCrossRefGoogle Scholar
  12. Heitkemper DT, Vela NP, Stewart KR, Westphal CS (2001) Determination of total and speciated arsenic in rice by ion chromatography and inductively coupled plasma mass spectrometry. J Anal Atom Spectrom 16:299–306CrossRefGoogle Scholar
  13. Jorhem L, Astrand C, Sundstrom B, Baxter M, Stokes P, Lewis J, Grawe KP (2008) Elements in rice from Swedish market: 1. Cadmium, lead and arsenic (total and inorganic). Food Addit Contam 25:284–292CrossRefGoogle Scholar
  14. Juhasz AL, Smith E, Weber J, Rees M, Rofe A, Kuchel T, Sansom L, Naidu R (2006) In vivo assessment of arsenic bioavailability in rice and its significance for human health risk assessment. Environ Health Perspect 114:1826–1831PubMedGoogle Scholar
  15. Lamont WH (2003) Concentration of inorganic arsenic in samples of white rice from the United States. J Food Compos Anal 16(6):687–695. doi:10.1016/S0889-1575(03)00097-8CrossRefGoogle Scholar
  16. Li RY, Ago Y, Liu WJ, Mitani N, Feldmann J, McGrath SP, Ma JF, Zhao FJ (2009) The rice aquaporin Lsi1 mediates uptake of methylated arsenic species. Plant Physiol 150:2071–2080PubMedCrossRefGoogle Scholar
  17. Lin HT, Wong SS, Li GC (2004) Heavy metal content of rice and shellfish in Taiwan. J Food Drug Anal 12:167–174Google Scholar
  18. Liu CW, Lin CC, Jang CS, Sheu GR, Tsui L (2009) Arsenic accumulation by rice grown in soil treated with roxarsone. J Plant Nutr Soil Sci 172:550–556CrossRefGoogle Scholar
  19. Lombi E, Susini J (2009) Synchrotron-based techniques for plant and soil science: opportunities, challenges and future perspectives. Plant Soil 320:1–35CrossRefGoogle Scholar
  20. Lombi E, Scheckel KG, Pallon J, Carey AM, Zhu YG, Meharg AA (2009) Speciation and distribution of arsenic and localization of nutrients in rice grains. New Phytol 184:193–201CrossRefGoogle Scholar
  21. Lu Y, Adomako EE, Solaiman ARM, Islam RM, Deacon C, Williams PN, Rahman GKMM, Meharg AA (2009) Baseline soil variation is a major factor in arsenic accumulation in Bengal Delta paddy rice. Environ Sci Technol 43:1724–1729PubMedCrossRefGoogle Scholar
  22. Meharg AA, Hartley-Whitaker J (2002) Arsenic uptake and metabolism in arsenic resistant and non-resistant plant species. New Phytol 154:29–43CrossRefGoogle Scholar
  23. Meharg AA, Raab A (2010) Getting to the bottom of arsenic standards and guidelines. Environ Sci Technol 44:4395–4399PubMedCrossRefGoogle Scholar
  24. Meharg AA, Rahman Md M (2003) Arsenic contamination of Bangladesh paddy field soils: implications for rice contribution to arsenic consumption. Environ Sci Technol 37:229–234PubMedCrossRefGoogle Scholar
  25. Meharg AA, Sun G, Williams PN, Adamako E, DeaconC ZhuYG, Feldmann J, Raab A (2008a) Inorganic arsenic levels in baby rice are of concern. Environ Pollut 152:746–749PubMedCrossRefGoogle Scholar
  26. Meharg AA, Deacon C, Campbell RCJ, Carey A-M, Williams PN, Feldmann J, Raab A (2008b) Inorganic arsenic levels in rice milk exceed EU and US drinking water standards. J Environ Monit 10:428–431PubMedCrossRefGoogle Scholar
  27. Meharg AA, Williams PN, Schekel K, Lombi E, Feldmann J, Raab A, Zhu YG, Gault A, Islam R (2008c) Speciation of arsenic differs between white and brown rice grain. Environ Sci Technol 42:1051–1057PubMedCrossRefGoogle Scholar
  28. Meharg AA, Williams PN, Adamako E, Lawgali YY, Deacon C, Villada A, Cambell RCJ, Sun GX, Zhu YG, Feldmann J, Raab A, Zhao FJ, Islam R, Hossain S, Yanai J (2009) Geographical variation in total and inorganic arsenic content of polished (white) rice. Environ Sci Technol 43:1612–1617PubMedCrossRefGoogle Scholar
  29. Munoz O, Diaz OP, Leyton I, Nunez N, Devesa V, Suner MA, Velez D (2002) Vegetables collected in the cultivated Andean area of northern Chile: total and inorganic arsenic contents in raw vegetables. J Agric Food Chem 50:642–647PubMedCrossRefGoogle Scholar
  30. National Research Council (2001) Arsenic in drinking water – 2001 update. National Academy Press, Washington, DCGoogle Scholar
  31. Norton GJ, Islam MR, Deacon CM, Zhao FJ, Stroud JL, McGrath SP, Islam S, Jahiruddin M, Feldmann J, Price AH, Meharg AA (2009) Identification of low inorganic and total grain arsenic rice cultivars from Bangladesh. Environ Sci Technol 43:6024–6030CrossRefGoogle Scholar
  32. Raab A, Feldmann J, Meharg AA (2004) The nature of arsenic – phytochelatins complexes in Holcus lanatus and Pteris cretica. Plant Physiol 134:1113–1122PubMedCrossRefGoogle Scholar
  33. Raab A, Baskaran C, Feldmann J, Meharg AA (2008) Cooking rice in a high water to rice ratio reduces inorganic arsenic content. J Environ Monit 11:41–44PubMedCrossRefGoogle Scholar
  34. Schoof RA, Yost LJ, Eickhoff J, Crecelius EA, Cragin DW et al (1999) A market basket survey of inorganic arsenic in food. Food Chem Toxicol 37:839–846PubMedCrossRefGoogle Scholar
  35. Signes-Pastor AJ, Deacon C, Harris P, Carbonell-Barrachina AA, Meharg AA (2009) Arsenic speciation in Japanese rice drinks and condiments. J Environ Monit 11:1930–1934PubMedCrossRefGoogle Scholar
  36. Sun GX, Williams PN, Carey AM, Zhu YG, Deacon C et al (2008) Inorganic arsenic in rice bran and its products are an order of magnitude higher than in bulk grain. Environ Sci Technol 42:7542–7546PubMedCrossRefGoogle Scholar
  37. Sun G-X, Zhu YG, Williams PN, Deacon C, Meharg AA (2009) Survey of arsenic and its speciation in cereal rice products. Environ Int 35:473–475PubMedCrossRefGoogle Scholar
  38. Torres-Escribano S, Leal M, Velez D, Montoro R (2008) Total and inorganic arsenic concentrations in rice sold in Spain, effect of cooking, and risk assessments. Environ Sci Technol 42:3867–3872PubMedCrossRefGoogle Scholar
  39. Williams PN, Price AH, Raab A, Hossain SA, Feldmann J, Meharg AA (2005) Variation in arsenic speciation and concentration in paddy rice related to dietary exposure. Environ Sci Technol 39:5531–5540PubMedCrossRefGoogle Scholar
  40. Williams PN, Islam MR, Adomako EE, Raab A, Hossain SA et al (2006) Increase in rice grain arsenic for regions of Bangladesh irrigating paddies with elevated arsenic in groundwaters. Environ Sci Technol 40:4903–4908PubMedCrossRefGoogle Scholar
  41. Williams PN, Raab A, Feldmann J, Meharg AA (2007a) Market basket survey shows elevated levels of as in South Central US processed rice compared to California: consequences for human dietary exposure. Environ Sci Technol 41:2178–2183PubMedCrossRefGoogle Scholar
  42. Williams PN, Villada A, Deacon C, Raab A, Figuerola J et al (2007b) Greatly enhanced arsenic shoot assimilation in rice leads to elevated grain levels compared to wheat and barley. Environ Sci Technol 41:6854–6859PubMedCrossRefGoogle Scholar
  43. Williams PN, Lei M, Sun G-X, Huang Q, Lu Y, Deacon C, Meharg AA, Zhu Y-G (2009) Occurrence and partitioning of cadmium, arsenic and lead in mine impacted paddy rice: Hunan, China. Environ Sci Technol 43:637–642PubMedCrossRefGoogle Scholar
  44. World Health Organization (2004) IARC, Working Group on some drinking water disinfectants and contaminants, including arsenic, vol 84. Lyon. Monograph 1Google Scholar
  45. Xu XY, McGrath SP, Meharg A, Zhao FJ (2008) Growing rice aerobically markedly decreases arsenic accumulation. Environ Sci Technol 42:5574–5579PubMedCrossRefGoogle Scholar
  46. Zavala YJ, Duxbury JM (2008) Arsenic in rice: I. Estimating normal levels of total arsenic in rice grain. Environ Sci Technol 42:3856–3860PubMedCrossRefGoogle Scholar
  47. Zavala YJ, Gerads R, Gürleyük H, Duxbury JM (2008) Arsenic in rice: II. Arsenic speciation in USA grain and implications for human health. Environ Sci Technol 42:3861–3866PubMedCrossRefGoogle Scholar
  48. Zhao FJ, Ma JF, Meharg AA, McGrath SP (2009) Arsenic uptake and metabolism in plants. New Phytol 181:777–794PubMedCrossRefGoogle Scholar
  49. Zhu Y-G, Sun G-X, Lei M, Teng M, Liu Y-X, Chen N-C, Hong W-L, Carey AM, Meharg AA, Williams PN (2008) High percentage inorganic arsenic content of mining impacted and nonimpacted Chinese rice. Environ Sci Technol 42:5008–5013PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media B.V.  2012

Authors and Affiliations

  • Andrew A. Meharg
    • 1
  • Fang-Jie Zhao
    • 2
    • 3
  1. 1.University of AberdeenAberdeenUK
  2. 2.Rothamsted ResearchHarpendenUK
  3. 3.Nanjing Agricultural UniversityNanjingChina

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