Abstract
The stomach is unique in that ICC have a different distribution in proximal and distal regions of the same organ. ICC located within the circular (ICC-CM) and longitudinal (ICC-LM) muscle layers are densely distributed throughout the thick circular and longitudinal muscle layers of the cardia, fundus and of the proximal half of the corpus in the mouse, rat and guinea-pig. In contrast, ICC associated with the myenteric plexus (ICC-MP) are completely lacking from the space between the circular and longitudinal muscle layers in these regions. ICC-MP emerge in the mid-corpus and become well-developed in the distal region of the corpus. ICC-MP are particularly dense in the pyloric antrum. Another characteristic feature of the pylorus is the presence of ICC at the submucosal border of the circular muscle layer (ICC-SM).
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© 2012 Springer Science+Business Media B.V.
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Komuro, T. (2012). Stomach. In: Atlas of Interstitial Cells of Cajal in the Gastrointestinal Tract. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2917-9_2
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DOI: https://doi.org/10.1007/978-94-007-2917-9_2
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Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-007-2916-2
Online ISBN: 978-94-007-2917-9
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