Non-equilibrium Air Plasma for Wound Bleeding Control

  • Spencer P. Kuo
  • Cheng-Yen Chen
  • Chuan-Shun Lin
  • Shu-Hsing Chiang
Conference paper
Part of the NATO Science for Peace and Security Series A: Chemistry and Biology book series (NAPSA)


A low temperature non-equilibrium air plasma spray is tested as a blood coagulator. Emission spectroscopy of the plasma effluent indicates that it carries abundant reactive atomic oxygen (RAO), which can activate erythrocyte – platelet interactions to enhance blood coagulation for plug formation. Tests of the device for wound bleeding control were performed on pigs. Four types of wounds, straight cut and cross cut in the ham area, a hole in an ear saphenous vein, and a cut to an ear artery, were examined. The results showed that this plasma spray could effectively stop the bleeding and reduced the bleeding time considerably. Post-Operative observation of straight cut and cross cut wound healing was carried out. It was found that the plasma treatment had a positive impact on wound healing, in particular, of the cross cut wound; its healing time was shortened by a half.


Plasma Spray Plasma Plume Tissue Oxygen Tension Plasma Treatment Time Dissociative Attachment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



We are grateful to Alessandro Betti for fabricating the plasma spray device. This work was supported in part by a NYU-Poly seed Grant and in part by Adventix Technologies Inc.


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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • Spencer P. Kuo
    • 1
  • Cheng-Yen Chen
    • 1
  • Chuan-Shun Lin
    • 2
  • Shu-Hsing Chiang
    • 2
  1. 1.Department of Electrical and Computer EngineeringPolytechnic Institute of New York UniversityBrooklynUSA
  2. 2.Department of Animal Science and BiotechnologyTung Hai UniversityTaichungTaiwan ROC

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