Abstract
Since the hair follicle undergoes cycles of degeneration and regeneration throughout life, it has been assumed that hair follicle growth is controlled by stem cells. Currently, the best characterized hair follicle stem cell population is the bulge stem cell which resides in a discrete microenvironment called the bulge. Bulge stem cells have the capacity to differentiate into all epithelial components of the hair follicle, and also participate in the repair of the skin after injury. The ability to purify and culture human hair follicle bulge stem cells offers fascinating therapeutic potential for alopecia as well as for epithelial tissue engineering.
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Zhao, L., Hantash, B.M. (2012). Human Hair Follicle Stem Cells: Markers, Selection and Prospective Clinical Applications. In: Hayat, M. (eds) Stem Cells and Cancer Stem Cells, Volume 4. Stem Cells and Cancer Stem Cells, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2828-8_17
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DOI: https://doi.org/10.1007/978-94-007-2828-8_17
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