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Neuroblastoma Mouse Model

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Book cover Neuroblastoma

Part of the book series: Pediatric Cancer ((PECA,volume 1))

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Abstract

Neuroblastoma, which arises from sympathetic neural precursors, is the most common childhood cancer. The prognosis of advanced neuroblastoma remains poor even with intensive therapy. To develop new therapeutic agents, researchers have explored the molecular pathogenesis of neuroblastoma. Animal models of neuroblastoma are an indispensable tool for neuroblastoma research. This chapter reviews neuroblastoma mouse models, ranging from classic xenograft models to recently-developed genetically-engineered mouse models, discusses the insight obtained from these mouse models.

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Authors and Affiliations

  1. Ghrelin Research Project, Translation Research Center, Kyoto University Hospital, Kyoto, 606-8507, Japan

    Hiroshi Iwakura & Takashi Akamizu

Authors
  1. Hiroshi Iwakura
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  2. Takashi Akamizu
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Correspondence to Hiroshi Iwakura .

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Editors and Affiliations

  1. , Kean University, Room 213, Library building, Morris Avenue 1000, Union, 07083, New Jersey, USA

    M.A. Hayat

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Iwakura, H., Akamizu, T. (2012). Neuroblastoma Mouse Model. In: Hayat, M. (eds) Neuroblastoma. Pediatric Cancer, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2418-1_4

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