Cartilage Injuries: Role of Implantation of Human Stem/Progenitor Cells

  • Yang Zi Jiang
  • Tong Tong
  • Boon Chin Heng
  • Hong Wei Ouyang
Part of the Stem Cells and Cancer Stem Cells book series (STEM, volume 3)


As articular cartilage has very limited self-repair capability, the repair and regeneration of damaged cartilage is a major challenge. This chapter aims to present the potential seed cell sources that can be utilized for cartilage regeneration, such as autologous chondrocytes (hACs), mesenchymal stem cells (MSCs), embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). One of the promising candidate is cartilage stem/progenitor cell (CSPCs). Current scientific research has demonstrated the existence, definition and niche of CSPCs. The clinical applications of CSPCs show much promise for cartilage regeneration.


hACs MSCs ESCs iPSCs CSPCs Articular cartilage 


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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • Yang Zi Jiang
    • 1
  • Tong Tong
    • 1
  • Boon Chin Heng
    • 1
  • Hong Wei Ouyang
    • 1
  1. 1.School of Medicine, Center for Stem Cell and Tissue EngineeringZhejiang UniversityHangzhouChina

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