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Biomedical Applications of Induced Pluripotent Stem Cells

  • Vimal Selvaraj
Chapter
Part of the Stem Cells and Cancer Stem Cells book series (STEM, volume 3)

Abstract

The generation of induced pluripotent stem (iPS) cells from differentiated somatic cells offers innovative biomedical applications that are significantly advancing human medicine. Patient-specific iPS cells can self-renew indefinitely and serve as a limitless source of autologous cells to treat a number of human degenerative diseases without the risk of immune rejection. In the near-term, iPS cells from patients with inheritable disorders will offer novel platforms for dissecting disease mechanisms, identifying new molecular therapeutic targets and pharmacological/toxicological testing for drug discovery. But several challenges in validating safety of iPS cells exist before its potential in clinical therapeutics can be realized.

Keywords

iPS Somatic cell SCNT ES Pluripotency Tissue 

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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  1. 1.Department of Animal ScienceCornell UniversityIthacaUSA

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