Stress Ecology pp 107-130 | Cite as

Heat Shock Proteins: The Minimal, but Universal, Stress Proteome

  • Christian E. W. Steinberg


The initial observation that led to the discovery of the heat shock proteins (HSPs) was that heat shock generated focal swellings or “puffs” on chromosomes of Drosophila salivary glands (Roberts et al. 2010). Such swellings were recognized as indicating that genes were being activated in those areas of the genome to give rise to their encoded proteins. These therefore became known as the “heat shock loci” and were initially considered a phenomenon unique to fruitflies. It was not until 1974 that these loci were proven the sites of transcriptional induction of genes encoding for a particular group of proteins, which were designated HSPs. It was even longer before it was recognized that they occurred in mammals and indeed at all evolutionary levels (Lindquist and Craig 1988).


Humic Substance Cold Acclimation Heat Shock Response Antarctic Fish Heat Stress Response 
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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  1. 1.Department of Biology Laboratory of Freshwater and Stress EcologyHumboldt-Universität zu BerlinBerlinGermany

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