Siraitia grosvenorii

  • T. K. Lim


The species is native to southern China – in the south-western Chinese province of Guangxi (mostly in the mountains of Guilin), as well as in Guangdong, Guizhou, Hunan and Jiangxi and Northern Thailand. Extensively cultivated by the Zhong enthic people in southern China.


Triterpene Glycoside Blood Lipid Level Piperonyl Butoxide Sweet Element Mogroside Versus 
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Selected References

  1. Akihisa T, Hayakawa Y, Tokuda H, Banno N, Shimizu N, Suzuki T, Kimura Y (2007) Cucurbitane glycosides from the fruits of Siraitia grosvenorii and their inhibitory effects on Epstein-Barr virus activation. J Nat Prod 70(5):783–788PubMedCrossRefGoogle Scholar
  2. Anonymous (2004) A brief history of Luo Han Fruit (Luo Han Guo).
  3. Bu CW (2004) Studies on processing functus Siraitia grosvenorii whisk in yoghurt. China Dairy Ind 32(1):35–37Google Scholar
  4. Chen WJ, Wang J, Qi XY, Xie BJ (2007) The antioxidant activities of natural sweeteners, mogrosides, from fruits of Siraitia grosvenori. Int J Food Sci Nutr 58(7):548–556Google Scholar
  5. Hewett EW (2008) Postharvest requirements for underutilized tropical and subtropical fruit crops. Acta Hortic ISHS 770:95–102Google Scholar
  6. Hsu H-Y, Chen Y-P, Shen S-J, Hsu C-S, Chen C-C, Chang H-C (1986) Oriental materia medica: a concise guide. Oriental Healing Arts Institute, Long Beach, 933 ppGoogle Scholar
  7. Hu S-Y (2005) Food plants of China. The Chinese University Press, Hong Kong, 844 ppGoogle Scholar
  8. Huang CP, Li J, Liu QY, Lu XW, Meng AP, Zhu SJ (2010) Studies on the polysaccharide SGPS2 from the fruits of Siraitia grosvenorii. Zhong Yao Cai 33(3):376–379, In ChineseGoogle Scholar
  9. Jia Z, Yang X (2009) A minor, sweet cucurbitane glycoside from Siraitia grosvenorii. Nat Prod Commun 4(6):769–772Google Scholar
  10. Konoshima T, Takasaki M (2002) Cancer-chemopreventive effects of natural sweeteners and related compounds. Pure Appl Chem 74(7):1309–1316Google Scholar
  11. Lee C-H (1975) Intense sweetener from Lo Han Kuo (Momordica grosvenori). Experientia 31:533–534Google Scholar
  12. Li D, Ikeda T, Matsuoka N, Nohara T, Zhang H, Sakamoto T, Nonaka G (2006) Cucurbitane glycosides from unripe fruits of Lo Han Kuo (Siraitia grosvenori). Chem Pharm Bull Tokyo 54(10):1425–1428Google Scholar
  13. Lin GP, Jiang T, Hu XB, Qiao XH, Tuo QH (2007) Effect of Siraitia grosvenorii polysaccharide on glucose and lipid of diabetic rabbits induced by feeding high fat/high sucrose chow. Exp Diabetes Res 2007:67435Google Scholar
  14. Lu F, Liu J, Huang Y, Li D (2008) Simultaneous determination of six cucurbitane triterpene glycosides in Siraitia grosvenorii fruits using high performance liqid chromatography. Se Pu 26(4):504–508, In ChineseGoogle Scholar
  15. Marone PA, Borzelleca JF, Merkel D, Heimbach JT, Kennepohl E (2008) Twenty eight-day dietary toxicity study of Luo Han fruit concentrate in Hsd:SD® rats. Food Chem Toxicol 46(3):910–919Google Scholar
  16. Matsumoto S, Jin M, Dewa Y, Nishimura J, Moto M, Murata Y, Shibutani M, Mitsumori K (2009) Suppressive effect of Siraitia grosvenorii extract on dicyclanil-promoted hepatocellular proliferative lesions in male mice. J Toxicol Sci 34(1):109–118Google Scholar
  17. Mu J (1998) Anti-cariogenicity of maceration extract of Momordica grosvenori: laboratory study. Zhonghua Kou Qiang Yi Xue Za Zhi 33(3):183–185, In ChineseGoogle Scholar
  18. Murata Y, Ogawa T, Suzuki YA, Yoshikawa S, Inui H, Sugiura M, Nakano Y (2010) Digestion and absorption of Siraitia grosvenori triterpenoids in the rat. Biosci Biotechnol Biochem 74(3):673–676Google Scholar
  19. Qi XY, Chen WJ, Zhang LQ, Xie BJ (2008) Mogrosides extract from Siraitia grosvenori scavenges free radicals in vitro and lowers oxidative stress, serum glucose, and lipid levels in alloxan-induced diabetic mice. Nutr Res 28(4):278–284Google Scholar
  20. Qin X, Xiaojian S, Ronggan L, Yuxian W, Zhunian T, Shouji G, Heimbach J (2006) Subchronic 90-day oral (gavage) toxicity study of a Luo Han Guo mogroside extract in dogs. Food Chem Toxicol 44(12):2106–2109Google Scholar
  21. Shi H, Hiramatsu M, Komatsu M, Kayama T (1996) Antioxidant property of Fructus Momordicae extract. Biochem Mol Biol Int 40(6):1111–1121Google Scholar
  22. Si JY, Chen DH, Tu GZ (2005) Siraitic acid F, a new nor-cucurbitacin with novel skeleton, from the roots of Siraitia grosvenorii. J Asian Nat Prod Res 7(1):37–41Google Scholar
  23. Song F, Qi X, Chen W, Jia W, Yao P, Nussler AK, Sun X, Liu L (2007) Effect of Momordica grosvenori on oxidative stress pathways in renal mitochondria of normal and alloxan-induced diabetic mice. Involvement of heme oxygenase-1. Eur J Nutr 46(2):61–69Google Scholar
  24. Suzuki YA, Murata Y, Inui H, Sugiura M, Nakano Y (2005) Triterpene glycosides of Siraitia grosvenori inhibit rat intestinal maltase and suppress the rise in blood glucose level after a single oral administration of maltose in rats. J Agric Food Chem 53(8):2941–2946Google Scholar
  25. Suzuki YA, Tomoda M, Murata Y, Inui H, Sugiura M, Nakano Y (2007) Antidiabetic effect of long-term supplementation with Siraitia grosvenori on the spontaneously diabetic Goto-Kakizaki rat. Br J Nutr 97(4):770–775Google Scholar
  26. Swingle WT (1941) Momordica grosvenori sp. nov. the source of the Chinese Lo han kuo. J Arnold Arbor 22:197–203Google Scholar
  27. Takasaki M, Konoshima T, Murata Y, Sugiura M, Nishino H, Tokuda H, Matsumoto K, Kasai R, Yamasaki K (2003) Anticarcinogenic activity of natural sweeteners, cucurbitane glycosides, from Momordica grosvenori. Cancer Lett 198(1):37–42Google Scholar
  28. Takeo E, Yoshida H, Tada N, Shingu T, Matsuura H, Murata Y, Yoshikawa S, Ishikawa T, Nakamura H, Ohsuzu F, Kohda H (2002) Sweet elements of Siraitia grosvenori inhibit oxidative modification of low-density lipoprotein. J Atheroscler Thromb 9(2):114–120Google Scholar
  29. Tsang KY, Ng TB (2001) Isolation and characterization of a new ribosome inactivating protein, momorgrosvin, from seeds of the monk’s fruit Momordica grosvenorii. Life Sci 68(7):773–784Google Scholar
  30. Ukiya M, Akihisa T, Tokuda H, Toriumi M, Mukainaka T, Banno N, Kimura Y, Hasegawa J, Nishino H (2002) Inhibitory effects of cucurbitane glycosides and other triterpenoids from the fruit of Momordica grosvenori on Epstein-Barr virus early antigen induced by tumor promoter 12-O-tetradecanoylphorbol-13-acetate. J Agric Food Chem 50(23):6710–6715Google Scholar
  31. Yasuno H, Nishimura J, Dewa Y, Muguruma M, Takabatake M, Murata Y, Shibutani M, Mitsumori K (2008) Modifying effect of Siraitia grosvenorii extract on piperonyl butoxide-promoted hepatocarcinogenesis in rats. J Toxicol Sci 33(2):197–207Google Scholar
  32. Zhang L-Q, Qi X-Y, Chen W-J, Song Y-F (2006) Effect of mogroside extracts on blood glucose, blood lipid and antioxidation of hyperglycemic mice induced by Alloxan. Chin Pharm Bull 22(2):237–240Google Scholar
  33. Zheng Y, Liu Z, Ebersole J, Huang CB (2009) A new antibacterial compound from Luo Han Kuo fruit extract (Siraitia grosvenori). J Asian Nat Prod Res 11(8):761–765Google Scholar

Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • T. K. Lim
    • 1
  1. 1.ChisholmAustralia

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