Cucurbita maxima

  • T. K. Lim


C. maxima is a native of temperate South America – Chile, Argentina, Bolivia and Uruguay. Cucurbita maxima is the only species which originated in South America.


Trypsin Inhibitor Ascorbate Oxidase Total Carotenoid Content Pumpkin Seed Cucurbita Maximum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Selected References

  1. Amorim CZ, Marques AD, Cordeiro RS (1991) Screening of the antimalarial activity of plants of the Cucurbitaceae family. Mem Inst Oswaldo Cruz 86(Suppl 2):177–180Google Scholar
  2. Anderson JF (1987) Composition of the floral odor of Cucurbita maxima Duchesne (Cucurbitaceae). J Agric Food Chem 35:60–62Google Scholar
  3. Arima HK, Rodríguez-Amaya DB (1990) Carotenoid composition and vitamin A value of a squash and a pumpkin from northeastern Brazil. Arch Latinoam Nutr 40(2):284–292Google Scholar
  4. Attarde DL, Kadu SS, Chaudhari BJ, Kale SS, Bhamber RS (2010) In vitro antioxidant activity of pericarp of Cucurbita maxima Duch. ex Lam. Int J Pharm Tech Res 2(2):1533–1538Google Scholar
  5. Azevedo-Meleiro CH, Rodriguez-Amaya DB (2007) Qualitative and quantitative differences in carotenoid composition among Cucurbita moschata, Cucurbita maxima, and Cucurbita pepo. J Agric Food Chem 55(10):4027–4033Google Scholar
  6. Bates DM, Robinson RW, Jeffrey C (eds.) (1990) Biology and utilization of the Cucurbitaceae. Cornell University Press, New York, 485 ppGoogle Scholar
  7. Bown D (1995) Encyclopaedia of herbs and their uses. Dorling Kindersley, London, 424 ppGoogle Scholar
  8. Burkill HM (1985) The useful plants of West Tropical Africa. Vol. 1. Families A–D. Royal Botanic Gardens, Kew, 960 ppGoogle Scholar
  9. Cai M, Gong Y, Prakash O, Krishnamoorthi R (1995) Reactive-site hydrolyzed Cucurbita maxima trypsin inhibitor-V: function, thermodynamic stability, and NMR solution structure. Biochemistry 34(38):12087–12094Google Scholar
  10. Chiej R (1984) Encyclopaedia of medicinal plants. MacDonald, London, 447 ppGoogle Scholar
  11. Chigumira Ngwerume F, Grubben GJH (2004) Cucurbita maxima Duchesne. In: Grubben GJH, Denton OA (eds.) PROTA 2: vegetables/légumes. [CD-Rom]. PROTA, Wageningen, NetherlandsGoogle Scholar
  12. Chigumira Ngwerume F, Mvere B (1999) The status of traditional leafy vegetables in Zimbabwe. In: Chweya J, Eyzaguire PB (eds) The biodiversity of traditional leafy vegetables. IPGRI, Rome, pp 155–171Google Scholar
  13. Chopra RN, Nayar SL, Chopra IC (1986) Glossary of Indian medicinal plants (Including the supplement). Council Scientific Industrial Research, New Delhi, 330 ppGoogle Scholar
  14. Cruz RCB, Meurer CD, Silva EJ, Schaefer C, Santos ARS, Cruz AB, Filho VC (2006) Toxicity evaluation of Cucurbita maxima seed extract in mice. Pharm Biol 44(4):301–303Google Scholar
  15. Dannenhoffer JM, Suhr RC, Thompson GA (2001) Phloem-specific expression of the pumpkin fruit trypsin inhibitor. Planta 212(2):155–162Google Scholar
  16. Díaz Obregón D, Lloja Lozano L, Carbajal Zúñiga V (2004) Preclinical studies of Cucurbita maxima (pumpkin seeds) a traditional intestinal antiparasitic in rural urban areas. Rev Gastroenterol Perú 24:323–327Google Scholar
  17. Glew RH, Glew RS, Chuang L-T, Huang Y-S, Millson M, Constans D, Vanderjagt DJ (2006) Amino acid, mineral and fatty acid content of pumpkin seeds (Cucurbita spp.) and Cyperus esculentus nuts in the Republic of Niger. Plant Foods Hum Nutr 61(2):51–56Google Scholar
  18. Hojima Y, Pierce JV, Pisano JJ (1982) Pumpkin seed inhibitor of human factor XIIa (activated Hageman factor) and bovine trypsin. Biochemistry 21(16):3741–3746Google Scholar
  19. Holland B, Unwin ID, Buss DH (1991) Vegetables herbs and spices, Fifth supplement to McCance and Widdowson’s the composition of foods. Royal Society of Chemistry, Cambridge, 163 ppGoogle Scholar
  20. Kreck M, Kürbel P, Ludwig M, Paschold P, Dietrich H (2006) Identification and quantification of carotenoids in pumpkin cultivars (Cucurbita maxima L.) and their juices by liquid chromatography with ultraviolet-diode array detection. J Appl Bot Food Qual 80(2):93–97Google Scholar
  21. Krishnamoorthi R, Gong YX, Richardson M (1990) A new protein inhibitor of trypsin and activated Hageman factor from pumpkin (Cucurbita maxima) seeds. FEBS Lett 273(1–2):163–167Google Scholar
  22. Leung W-TW, Busson F, Jardin C (1968) Food composition table for use in Africa. FAO, Rome, 306 ppGoogle Scholar
  23. Miró M (1995) Cucurbitacins and their pharmacological effects. Phytother Res 9(3):159–168Google Scholar
  24. Mullai K, Jebanesan A (2007) Larvicidal, ovicidal and repellent activities of the leaf extract of two cucurbitaceous plants against filarial vector Culex quinquefasciatus (Say) (Diptera: Culicidae). Trop Biomed 24(1):1–6Google Scholar
  25. Muntein E, Rotar I (2010) HPLC assessment of provitamin A carotenoids from Cucurbita maxima Duch. ex. Lm. (Mariţa cultivar) fruits. Res J Agric Sci 42(1):517–520Google Scholar
  26. Nowak K, Słomińska A, Polanowski A, Wieczorek M, Wilusz T (1981) Trypsin inhibitor III from squash seeds (Cucurbita maxima), its reactive site and proposed amino acid sequence. Hoppe Seylers Z Physiol Chem 362(7):1017–1019Google Scholar
  27. Ojiako OA, Igwe CU (2007) Nutritional and anti-nutritional compositions of Cleome rutidosperma, Lagenaria siceraria, and Cucurbita maxima seeds from Nigeria. J Med Food 10(4):735–738Google Scholar
  28. Parry J, Hao Z, Luther M, Su L, Zhou K, Yu LL (2006) Characterization of cold-pressed onion, parsley, cardamom, mullein, roasted pumpkin, and milk thistle seed oils. J Am Oil Chem Soc 83(10):847–854Google Scholar
  29. Porcher MH et al (1995–2020) Searchable world wide web multilingual multiscript plant name database. Published by The University of Melbourne, Australia.
  30. Porto TS, Marques PP, Porto CS, Moreira KA, Lima-Filho JL, Converti A, Pessoa A, Porto ALF (2010) Extraction of ascorbate oxidase from Cucurbita maxima by continuous process in perforated rotating disc contactor using aqueous two-phase systems. Appl Biochem Biotechnol 160(4):1057–1064Google Scholar
  31. Queiroz-Neto AD, Mataqueiro MI, Santana AE, Alessi AC (1994) Toxicologic evaluation of acute and subacute oral administration of Cucurbita maxima seed extracts to rats and swine. J Ethnopharmacol 43:45–51Google Scholar
  32. Rahman AHMM, Anisuzzaman M, Ahmed F, Rafiul Islam AKM, Naderuzzaman ATM (2008) Study of nutritive value and medicinal uses of cultivated cucurbits. J Appl Sci Res 4(5):555–558Google Scholar
  33. Rehm S, Wessels JH (1957) Bitter principles of the cucurbitaceae. VIII. – cucurbitacins in seedlings – occurrence, biochemistry and genetical aspects. J Sci Food Agric 8(12):687–691Google Scholar
  34. Robinson RW, Decker-Walters DS (1997) Cucurbits. CAB International, Wallingford, 226 ppGoogle Scholar
  35. Rozycki J, Kupryszewski G, Rolka K, Ragnarsson U, Zbyryt T, Krokoszynska I, Wilusz T (1994) Analogues of Cucurbita maxima trypsin inhibitor III (CMTI-III) with elastase inhibitory activity. Biol Chem Hoppe Seyler 375(4):289–291Google Scholar
  36. Rubaihayo EB (1997) Conservation and use of traditional vegetables in Uganda. In: Guarino L (ed.) Traditional African vegetables. Promoting the conservation and use of underutilized and neglected crops. 16. Proceedings of the IPGRI international workshop on genetic resources of traditional vegetables in Africa: conservation and use, ICRAF-HQ, Nairobi, 29–31 Aug 1995. Institute of Plant Genetics and Crop Plant Research, Gatersleben/International Plant Genetic Resources Institute, RomeGoogle Scholar
  37. U.S. Department of Agriculture, Agricultural Research Service (2010) USDA national nutrient database for standard reference, release 23. Nutrient data laboratory home page.
  38. Villasenor IM, Bartolome ALO, Daclan LC, Manatad AJG (1995) Microbiological and pharmacological studies on extracts of Cucurbita maxima. Phytother Res 9(5):376–378Google Scholar
  39. Villasenor IM, Lemon P, Palileo A, Bremner JB (1996) Antigenotoxic spinasterol from Cucurbita maxima flowers. Mutat Res 360(2):89–93Google Scholar
  40. Wen L, Lee I, Chen G, Huang JK, Gong Y, Krishnamoorthi R (1995) Changing the inhibitory specificity and function of Cucurbita maxima trypsin inhibitor-V by site-directed mutagenesis. Biochem Biophys Res Commun 207(3):897–902Google Scholar
  41. Widjaja EA, Sukprakarn S (1994) Cucurbita L. In: Siemonsma JS, Piluek K (eds.) Plant resources of South-East Asia No. 8. Vegetables. Pudoc Scientific, Wageningen, pp 160–165Google Scholar
  42. Wieczorek M, Otlewski J, Cook J, Parks K, Leluk J, Wilimowska-Pelc A, Polanowski A, Wilusz T, Laskowski M Jr (1986) The squash family of serine proteinase inhibitors. Amino acid sequences and association equilibrium constants of inhibitors from squash, summer squash, zucchini, and cucumber seeds. Biochem Biophys Res Commun 126(2):646–652Google Scholar
  43. Wilusz T, Wieczorek M, Polanowski A, Denton A, Cook J, Laskowski M Jr (1983) Amino-acid sequence of two trypsin isoinhibitors, ITD I and ITD III from squash seeds (Cucurbita maxima). Hoppe Seylers Z Physiol Chem 364(1):93–95Google Scholar

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© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • T. K. Lim
    • 1
  1. 1.ChisholmAustralia

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