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Epileptic Seizures and Supratentorial Brain Tumors in Children

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Tumors of the Central Nervous System, Volume 4

Part of the book series: Tumors of the Central Nervous System ((TCNS,volume 4))

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Abstract

Brain tumors represent about one third of the pediatric tumors. Epilepsy is overall associated with supratentorial brain tumors, that prevail in children under 3 years and over 10 years. Prevalence of seizures as first tumor symptom is 15–20%. In children under the 3 years of life, epilepsy is more frequent (until 70%), it can persists after the surgical intervention and in some cases an epileptic encephalopathy occurs. Epilepsy can began after surgery in other cases (10–40%), as a consequence of brain damage. Moreover, brain tumors are in a relevant percentage of cases (26–50%) the cause of a drug-resistant epilepsy, that can be successfully treated by surgery. The post surgical evolution is more favorable for patients with some particular tumor types (DNT, gangliogliomas). Pharmacological therapy of the epilepsy related with tumors is difficult, for an high frequency of side effects and of interactions with chemotherapy. The new AED are particularly promising not only for the favorable effect, but also for the lower incidence of side effects and of interactions.

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Authors and Affiliations

  1. Department of Neurosciences, Gaslini Children’s Hospital, 16147, Genoa, Italy

    Roberto Gaggero, Alessandro Consales, Francesca Fazzini, Maria Luisa Garrè & Pasquale Striano

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  1. Roberto Gaggero
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  2. Alessandro Consales
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  3. Francesca Fazzini
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  4. Maria Luisa Garrè
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  5. Pasquale Striano
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Correspondence to Roberto Gaggero .

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  1. , Kean University, Room 213, Library building, Morris Avenue 1000, Union, 07083, New Jersey, USA

    M.A. Hayat

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Gaggero, R., Consales, A., Fazzini, F., Garrè, M.L., Striano, P. (2012). Epileptic Seizures and Supratentorial Brain Tumors in Children. In: Hayat, M. (eds) Tumors of the Central Nervous System, Volume 4. Tumors of the Central Nervous System, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1706-0_3

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  • DOI: https://doi.org/10.1007/978-94-007-1706-0_3

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  • Print ISBN: 978-94-007-1705-3

  • Online ISBN: 978-94-007-1706-0

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