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Oxadiazoles

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Book cover Microwave-Induced Synthesis of Aromatic Heterocycles

Part of the book series: SpringerBriefs in Molecular Science ((GREENCHEMIST,volume 3))

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Abstract

Microwave assisted synthesis in organic chemistry is an important and a well established area of research due to a number of advantages over conventional heating methods. Further, nitrogen heterocycles of different ring sizes, with different substitution patterns and embedded in various molecular frameworks constitute extremely important structure classes in the search for bioactivity. Many compounds bearing five-membered heterocyclic rings in their structure have an extensive spectrum of pharmacological activities. Among them oxadiazoles and their derivatives have attracted considerable interest in material and medicinal chemistry as surrogates of carboxylic acids, esters and carboxamides. The various oxadiazole compounds have shown a wide array of biological activities in both agrochemical and pharmaceutical fields. The formation of this biologically important heterocyclic system under microwave conditions is described in this chapter.

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Authors and Affiliations

  1. Department of Chemistry, Aligarh Muslim University, Aligarh, India

    Abdul Rauf

  2. B-1, Liberty Homes, Opposite Abdullah College, Marris Road, Aligarh, 202 002, India

    Nida Nayyar Farshori

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  1. Abdul Rauf
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  2. Nida Nayyar Farshori
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Correspondence to Abdul Rauf .

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Rauf, A., Farshori, N.N. (2012). Oxadiazoles. In: Microwave-Induced Synthesis of Aromatic Heterocycles. SpringerBriefs in Molecular Science(), vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-1485-4_5

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