Mast Cells and Tumour Angiogenesis

  • Domenico Ribatti
  • Enrico Crivellato


Inflammatory cells regulate endothelial cell functions related to physiological angiogenesis as well as inflammatory and tumour-associated angiogenesis. It was Rudolf Virchow in 1863, who critically recognized the presence of inflammatory cells infiltrating neoplastic tissues and first established a causative connection between the “lymphoreticular infiltrate” at sites of chronic inflammation and cancer.


Papillary Thyroid Carcinoma Sodium Cromoglycate Thyroid Cancer Cell Microvascular Density Microvessel Count 
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Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  1. 1.Department of Human Anatomy and HistologyUniversity of Bari Medical School PoliclinicoBariItaly
  2. 2.Section of Anatomy Department of Experimental and Clinical MedicineUniversity of Udine Medical SchoolUdineItaly

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