Cross Selectivity Immunoaffinity and Applications for Lactoferrin Immunosensor

  • M. Tomassetti
  • E. Martini
  • L. Campanella
Conference paper
Part of the Lecture Notes in Electrical Engineering book series (LNEE, volume 91)


After recent research carried out by our team aimed at developing new immunosensors for lactoferrin, in the present note are reported the results of research carried out to determine the constant of affinity between Lactoferrin and the corresponding antibody (human anti-lactoferrin). In addition, a detailed investigation was made of immunosensor selectivity and the cross selectivity of the immunosensor developed towards the principal proteins present in milk which are considered as possible interference in Lactoferrin determination in milk and its derivatives, or in saliva.


Milk Sample Bovine Milk Passive Immunity Immunological Method Reliable Assay 
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Research funded by “La Sapienza” University of Rome, “Ateneo and University Projects”.


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    Campanella L, Martini E, Tomassetti M (2008) New immunosensor for lactoferrin determination in human milk and several pharmaceutical dairy milk products recommended for the unweaned diet. J Pharm Biomed Anal 48:278–287CrossRefGoogle Scholar
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    Campanella L, Martini E, Pintore M, Tomassetti M (2009) Determination of lactoferrin and immunoglobulin G in animal milks by new immunosensors. Sensors 9:2202–2221CrossRefGoogle Scholar
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    Campanella L, Martini E, Tomassetti M (2009) Further development of lactoferrin immunosensor. In: Abstract book of 13th international meeting RDPA, Milan, Italy, p 77, 9–12 Sept 2009Google Scholar

Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  1. 1.Department of ChemistryUniversity of Rome “La Sapienza”RomeItaly

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