Luminescent Porous Silicon Nanoparticles as Drug Carrier

  • Vera La Ferrara
  • Girolamo Di Francia
  • Giuseppe Fiorentino
Conference paper
Part of the Lecture Notes in Electrical Engineering book series (LNEE, volume 91)


In this work, the applicability of luminescent porous silicon (PS) nanoparticles as ascorbic acid (AA) carrier has been studied. PS nanoparticles have been realized reducing in multi-sized particles porous silicon free-standing film placed in deionized water by sonication and filtering through 0.45 ?m membrane. The PS nanoparticles are water-soluble and highly fluorescent. PS nanoparticles are loaded by AA, monitoring the fluorescence spectra by a spectrofluorimeter. Before assessing the loading of AA into PS nanoparticles dispersed in water, the emission stability of PS solution has been acquired. Once stabilized the signal and loaded the AA, the presence and the real absorption of AA onto PS nanoparticles has been evaluated from emission quenching of the silicon nanoparticles.


Ascorbic Acid Porous Silicon Emission Stability Efficient Drug Loading Porous Silicon Film 
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The authors gratefully acknowledge the Ministry of Universities and Research (MIUR) for financial support as part of Public-Private Laboratory TRIPODE (Technologies and Research for the application of polymers in electronics devices).


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Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  • Vera La Ferrara
    • 1
  • Girolamo Di Francia
    • 1
  • Giuseppe Fiorentino
    • 2
  1. 1.ENEA Research CenterPorticiItaly
  2. 2.Department of PhysicsUniversity “Federico II”NaplesItaly

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