Hepatic venous pressure gradient: the facts

  • Julio D. Vorobioff
  • Juan G. Abraldes
  • Roberto J. Groszmann

Abstract

Many of the clinical complications of cirrhosis are the direct consequences of the elevation of portal venous pressure (PVP). Portal hypertension is defined as a PVP of greater than the normal 5–10 mmHg. The degree of portal hypertension has been shown to correlate with the severity of liver disease, both functionally1 and histologically2, 3. However, direct portal venous measurement is invasive and cannot be routinely performed. As a surrogate, hepatic venous pressure gradient (HVPG) has been widely accepted as a measurement for PVP. The ease and safety of HVPG measurement has made it a valuable tool not only in the research arena, but also more and more in clinical practice.

Keywords

Portal Hypertension Hepatic Vein Cirrhotic Patient Esophageal Varix Variceal Bleeding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media Dordrecht 2004

Authors and Affiliations

  • Julio D. Vorobioff
  • Juan G. Abraldes
  • Roberto J. Groszmann
    • 1
  1. 1.VA Connecticut Healthcare SystemHepatic Hemodynamic Laboratory/111JWest HavenUSA

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