The Lipid World: From Catalytic and Informational Headgroups to Micelle Replication and Evolution Without Nucleic Acids

  • Arren Bar-Even
  • Barak Shenhav
  • Ran Kafri
  • Doron Lancet
Part of the Cellular Origin and Life in Extreme Habitats and Astrobiology book series (COLE, volume 7)

Abstract

A widespread notion is that life arose from a single molecular replicator, probably a self-copying polynucleotide, in an RNA World (Joyce, 2002). We have proposed an alternative Lipid World scenario as an early evolutionary step in the emergence of cellular life on Earth (Segre et al., 2001). This concept combines the potential chemical activities of lipids and other amphiphiles, with their capacity to undergo spontaneous self-organization into supramolecular structures, such as micelles and bilayers. In quantitative, chemically-realistic computer simulations of our Graded Autocatalysis Replication Domain (GARD) model (Segre et al., 1998), we have shown that prebiotic molecular networks, potentially existing within assemblies of lipid-like molecules, manifest a behavior similar to self reproduction or self-replication.

Keywords

Carbonaceous Chondrite Random Drift Catalytic Capacity Widespread Notion Orig Life 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media Dordrecht 2004

Authors and Affiliations

  • Arren Bar-Even
    • 1
  • Barak Shenhav
    • 1
  • Ran Kafri
    • 1
  • Doron Lancet
    • 1
  1. 1.Department of Molecular Genetics and the Crown Human Genome CenterWeizmann Institute of ScienceRehovotIsrael

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