Coronary Vascular Function in Stable and Unstable Angina
Angina pectoris and acute myocardial infarction are the main cardiac manifestations of atherosclerosis. Atherosclerosis is a pathological condition that underlies several important disorders including coronary artery disease, cerebrovascular disease, and diseases of the aorta and peripheral arterial circulation. Since Edward Jenner first attributed angina pectoris to coronary artery disease in 1786, there is a growing understanding about the pathophysiology of coronary artery disease and its complications. The first coronary artery disease manifestation in women is more likely to be angina, whereas in men it more often presents as a myocardial infarction. Even after surviving the acute stage of myocardial infarction, the incidence of re- infarction, sudden death, angina pectoris and cardiac failure are all substantial. Further innovations in diagnosis and treatment of coronary disease will undoubtedly improve the outlook of patients surviving the initial attack.
KeywordsNitric Oxide Methylene Blue Endothelial Dysfunction Endothelial Function Balloon Angioplasty
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