Fluorescence Spectroscopy of Crystalline Conformational Changes Under UV-Radiation
Cataract eye illness represents itself a great problem – about 60% of people over 60 overcome eyesight difficulties due to it. A complex investigation of cataract must be performed and some novel methods for diagnostics, control and treatment are to be developed. It has been discovered that one of the reasons that lead to cataract is absorption of UV radiation by eye lens. The proposed mechanism of cataract formation includes two stages: absorption of UV quanta by crystallins (eye lens proteins), conformational changes of cristallins and their consequent aggregation.