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Gamma-Frequency Synaptic Input Enhances Gain Modulation of the Layer V Pyramidal Neuron Model

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Advances in Cognitive Neurodynamics (II)

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Abstract

Cortical gamma frequency (30–80 Hz) oscillations have been suggested to underlie many aspects of cognitive functions. In this paper we compare the \(f-I\) curves modulated by gamma-frequency-modulated stimulus and Poisson synaptic input at distal dendrites of a layer V pyramidal neuron model. The results show that gamma-frequency distal input amplifies the sensitivity of neural response to basal input, and enhances gain modulation of the neuron.

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Authors and Affiliations

  1. Department of Electronic and Information Engineering, Hong Kong Polytechnic University, Kowloon, Hong Kong

    Xiumin Li & Michael Small

  2. RIKEN Brain Science Institute, Wako, 351-0198, Japan

    Kenji Morita

  3. Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK

    Hugh P.C. Robinson

Authors
  1. Xiumin Li
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  2. Kenji Morita
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  3. Hugh P.C. Robinson
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  4. Michael Small
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Corresponding author

Correspondence to Xiumin Li .

Editor information

Editors and Affiliations

  1. , Institute for Cognitive Neurodynamics, East China University of Science and Tec, Meilong Road 130, Shanghai, 200237, China, People's Republic

    Rubin Wang

  2. Fudan University, Shanghai, China, People's Republic

    Fanji Gu

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Li, X., Morita, K., Robinson, H.P., Small, M. (2011). Gamma-Frequency Synaptic Input Enhances Gain Modulation of the Layer V Pyramidal Neuron Model. In: Wang, R., Gu, F. (eds) Advances in Cognitive Neurodynamics (II). Springer, Dordrecht. https://doi.org/10.1007/978-90-481-9695-1_28

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