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Characterization of a Putative Hemagglutinin Gene in the Caprine Model for Brucellosis

  • Quinesha L. Perry
  • Sue D. Hagius
  • Joel V. Walker
  • Lauren Duhon
  • Philip H. ELZER
Conference paper
Part of the NATO Science for Peace and Security Series A: Chemistry and Biology book series (NAPSA, volume 00)

Abstract

With the completion of the genomic sequences of Brucella melitensis 16M and B. abortus 2308 and the vaccine strain RB51, a putative hemagglutinin gene was identified that is present in 16M and absent in B. abortus. The possibility of this hemagglutinin being a potential host specificity factor was evaluated via expression in trans in B. abortus 2308-QAE and RB51-QAE. Using the caprine brucellosis model, colonization and pathogenesis studies were performed to evaluate the strains.

Keywords

Abortion Rate Brucella Abortus Brucella Species Western Immunoblot Analysis Brucella Melitensis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Quinesha L. Perry
    • 1
  • Sue D. Hagius
    • 2
  • Joel V. Walker
    • 2
  • Lauren Duhon
    • 1
  • Philip H. ELZER
    • 1
    • 2
  1. 1.Department of Pathobiological Sciences, School of Veterinary MedicineLouisiana State UniversityBaton RougeUSA
  2. 2.Department of Veterinary ScienceLouisiana State University Agricultural CenterBaton RougeUSA

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