Characterization of a Putative Hemagglutinin Gene in the Caprine Model for Brucellosis

  • Quinesha L. Perry
  • Sue D. Hagius
  • Joel V. Walker
  • Lauren Duhon
  • Philip H. ELZER
Conference paper
Part of the NATO Science for Peace and Security Series A: Chemistry and Biology book series (NAPSA, volume 00)


With the completion of the genomic sequences of Brucella melitensis 16M and B. abortus 2308 and the vaccine strain RB51, a putative hemagglutinin gene was identified that is present in 16M and absent in B. abortus. The possibility of this hemagglutinin being a potential host specificity factor was evaluated via expression in trans in B. abortus 2308-QAE and RB51-QAE. Using the caprine brucellosis model, colonization and pathogenesis studies were performed to evaluate the strains.


Abortion Rate Brucella Abortus Brucella Species Western Immunoblot Analysis Brucella Melitensis 
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Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Quinesha L. Perry
    • 1
  • Sue D. Hagius
    • 2
  • Joel V. Walker
    • 2
  • Lauren Duhon
    • 1
  • Philip H. ELZER
    • 1
    • 2
  1. 1.Department of Pathobiological Sciences, School of Veterinary MedicineLouisiana State UniversityBaton RougeUSA
  2. 2.Department of Veterinary ScienceLouisiana State University Agricultural CenterBaton RougeUSA

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