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Application of Modern Techniques for Studying Bacterial Pathogens in Georgia

  • Ekaterine Zhgenti
  • Gvantsa Chanturia
  • Mariam Zakalashvili
  • Merab Kekelidze
Conference paper
Part of the NATO Science for Peace and Security Series A: Chemistry and Biology book series (NAPSA, volume 00)

Abstract

Over the last few years several molecular methods for rapid identification and fingerprinting of different pathogens have been applied at the National Center for Disease Control and Public health of Georgia (NCDC). These modern techniques strengthen the NCDC Georgia laboratory’s capabilities to rapidly respond to urgent public health threats and assist in the detection and tracking of these diseases. Application of genotyping techniques for investigation of NCDC Live Culture Collections enables Georgian public health scientists to determine the extent of strain variability as well as define the ability of new molecular techniques to characterize potential biothreat organisms circulating in the wild. Molecular methods, such as pulsed-field gel electrophoresis (PFGE), IS (insertion sequence) element fingerprinting, multiple-locus variable number tandem repeat analysis (MLVA) have been applied at NCDC in order to characterize bacterial isolates of Yersinis pestis and Francisella tularensis obtained from a variety of different foci. Such characterization has helped close a significant gap in our knowledge of strains present in this geographical region.

Keywords

Yersinia Pestis Francisella Tularensis Live Vaccine Strain Pestis Strain Variable Number Tandem Repeat Analysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Ekaterine Zhgenti
    • 1
  • Gvantsa Chanturia
    • 1
  • Mariam Zakalashvili
    • 1
  • Merab Kekelidze
    • 1
  1. 1.National Center for Diseases Control and Public Health of GeorgiaTbilisiGeorgia

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