A Study of the Protein Folding Problem by a Simulation Model

Chapter
Part of the Lecture Notes in Electrical Engineering book series (LNEE, volume 68)

Abstract

In this paper, we propose a simulation model to study the protein folding problem. We describe the main properties of proteins and describe the protein folding problem according to the existing approaches. Then, we propose to simulate the folding process when a protein is represented by an amino acid interaction network. This is a graph whose vertices are the proteins amino acids and whose edges are the interactions between them. We propose a genetic algorithm of reconstructing the graph of interactions between secondary structure elements which describe the structural motifs. The performance of our algorithms is validated experimentally.

Keywords

Genetic Algorithm Interaction Network Protein Data Bank Adjacency Matrix Secondary Structure Element 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  1. 1.Le Havre UniversityLe HavreFrance

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