Traditionally, Toxoplasma gondii encephalitis was diagnosed using brain radioimaging techniques, culture and serology. Mouse inoculation is the ‘gold standard’ but is rarely performed these days and culture in cell lines is relatively slow and lacks sensitivity . Serology is often used but it may be difficult to differentiate between past and current infection  and immunocompromised hosts may have a variable serological response. The detection of ring enhancing lesions in the brain by radioimaging is often used as an indicator of toxoplasmosis, however these signs may also be seen in lymphoma  and there are atypical presentations which make diagnosis difficult .
KeywordsParaffin Embed Vitreous Fluid Hydrolysis Probe Ocular Toxoplasmosis Ring Enhance Lesion
- 5.Ramsey RG, Gean AD (1997) Neuroimaging of AIDS. I. Central nervous system toxoplasmosis. Neuroimag Clin N Am 7:171–186Google Scholar