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Streptococcus pneumoniae

  • Bronwen Roy
  • Marcel Leroi
Chapter

Abstract

Pyogenic bacterial meningitis is a serious and sometimes fatal condition affecting the CNS. Globally, the three major bacterial pathogens causing meningitis are Haemophilus influenzae type b (HIB), Streptococcus pneumoniae and Neisseria meningitidis. Traditional laboratory diagnosis by culture of these pathogens is slow (>36 h) and non-culture based methods such as PCR are increasingly being utilised.

Keywords

Streptococcus Pneumoniae Neisseria Meningitidis Streptococcus Viridans Virulence Factor Gene Culture Negative Case 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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    Corless CE, Guiver M, Borrow R et al (2001) Simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae in suspected cases of meningitis and septicemia using real-time PCR. J Clin Microbiol 39:1553–1558PubMedCrossRefGoogle Scholar
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    Deutch S, Moller JK, Ostergaard L (2008) Combined assay for two-hour identification of Streptococcus pneumoniae and Neisseria meningitidis and concomitant detection of 16S ribosomal DNA in cerebrospinal fluid by real-time PCR. Scand J Infect Dis 40:607–614PubMedCrossRefGoogle Scholar
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    Whatmore AM, Efstratiou A, Pickerill AP et al (2000) Genetic relationships between clinical isolates of Streptococcus pneumoniae, Streptococcus oralis, and Streptococcus mitis: characterization of ‘Atypical’ pneumococci and organisms allied to S. mitis harboring S. pneumoniae virulence factor-encoding genes. Infect Immun 68:1374–1382PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  1. 1.Department of MicrobiologyNepean HospitalPenrithAustralia

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