Pyogenic bacterial meningitis is a serious and sometimes fatal condition affecting the CNS. Globally, the three major bacterial pathogens causing meningitis are Haemophilus influenzae type b (HIB), Streptococcus pneumoniae and Neisseria meningitidis. Traditional laboratory diagnosis by culture of these pathogens is slow (>36 h) and non-culture based methods such as PCR are increasingly being utilised.
KeywordsStreptococcus Pneumoniae Neisseria Meningitidis Streptococcus Viridans Virulence Factor Gene Culture Negative Case
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