Metastatic Solitary Malignant Brain Tumor: Magnetic Resonance Imaging

  • Nail Bulakbasi
  • Murat Kocaoglu
Part of the Methods of Cancer Diagnosis, Therapy and Prognosis book series (HAYAT, volume 8)


Brain metastasis is the second most common brain tumor in adults and still is a very common and devastating clinical problem for both cancer patients and treating physicians. Precise diagnosis of solitary brain metastasis is crucial for proper treatment planning and can directlyaffect patient morbidity and mortality. Although computed tomography is widely used for tumor diagnosis due to easy accessibility and low cost, magnetic resonance (MR) imaging is the method of choice for screening and differential diagnosis of solitary metastasis because of higher contrast resolution and availability of advanced imaging techniques such as diffusion-weighted and diffusion-tensor imaging, MR spectroscopy, perfusion and functional MR imaging. Major differential diagnosis of solitary metastasis includes high-grade glioma. Higher peritumoral rCBV values and Cho/Cr ratios of infiltrative gliomas, indicating existence of tumorcells, help to differentiate them from non-infiltrative metastasis. In conclusion, although the diagnosis of solitary brain tumors is still somewhat problematic, advanced MR imaging techniques provide valuable information to overcome the diagnostic hindrance and to increase effectiveness in therapy monitoring.


Apparent Diffusion Coefficient Brain Metastasis Fractional Anisotropy Magnetic Resonance Spectroscopy Mean Diffusivity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Netherlands 2011

Authors and Affiliations

  1. 1.Department of RadiologyGulhane Military Medical Academy and Military Medical FacultyAnkaraTurkey

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