Intra-axial Brain Tumors: Diagnostic Magnetic Resonance Imaging

  • Elias R. Melhem
  • Riyadh N. Alokaili
Part of the Methods of Cancer Diagnosis, Therapy and Prognosis book series (HAYAT, volume 8)


During the last century, central nervous system (CNS) imaging has witnessed a revolution with advances that have impacted all aspects of neuroscience practice in general and the management of intra-axial brain tumors in particular. In the pre-twentieth century era neurologists and neurosurgeons developed elaborate and sophisticated bedside examination techniques to gain insight into the calvarium. At the end of the nineteenth century and in the early twentieth century X-ray machines were developed and the ability to look through the opaque skull was a welcomed development by means of pneumoencephlography and later with cerebral angiography. In the 1970s, the way clinical neuroscience disciplines were practiced dramatically changed with the advent of X-ray computed tomography. Then in the 1980s, magnetic resonance imaging (MRI) was introduced. In the last 3 decades MRI became the imaging modality of choice for non-emergent neurological conditions, such as imaging of intra-axial brain masses, due to many advances including exquisite tissue contrast resolution and multi-planar capabilities.


Apparent Diffusion Coefficient Diffusion Tensor Imaging Blood Oxygen Level Dependant Proton Magnetic Resonance Spectroscopy Perfusion Magnetic Resonance Imaging 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Netherlands 2011

Authors and Affiliations

  1. 1.Department of RadiologyUniversity of Pennsylvania School of MedicinePhiladelphiaUSA

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