Screening Biochemical Markers for the Prevention of Coronary Heart Disease
Coronary heart disease (CHD) is among one of the major causes of deaths in Mauritius. It is important to screen biochemical markers, amongst other clinical and para-clinical tests, in view of the prevention of the disease. The study consisted of screening a random sample of 300 employees for total cholesterol above the desirable range (>5.17 mmol/l). A second fasting blood test was performed in those who had high total cholesterol. The lipid profile was performed using commercially available kits. The Total Cholesterol to High Density Lipoprotein Cholesterol ratio was calculated for identification of those at risk of CHD.
The findings showed an important prevalence of blood lipid abnormalities in the studied population, thus highlighting the need for screening for abnormal levels of these biochemical markers.
KeywordsCoronary Heart Disease Coronary Heart Disease Risk Coronary Heart Disease Risk Factor Workplace Setting Fast Blood Sugar Level
The authors are thankful to the staff of the Department of Medicine, University of Mauritius for technical support provided.
- 1.World Health Organization (2004) Global burden of coronary heart disease. In: Mackay J, Mensah G (eds) The atlas of heart disease and stroke, Part 3: the burden. World Health Organization, Geneva. http://www.who.int/cardiovascular_diseases/resources/atlas/en/. Accessed 8 Sept 2010
- 2.World Health Organization (2005) Preventing chronic diseases: a vital investment. World Health Organization, Geneva. http://www.who.int/. Accessed 8 Sept 2010
- 4.Gupta R, Gupta HP, Kumar N, Joshi AK, Gupta VP (1994) Lipoprotein lipids and the prevalence of hyperlipidaemia in rural India. J Cardiovasc Risk 1:179–184Google Scholar
- 5.Rafiei M, Boshtam M, Sarraf-Zadegan N (1999) Lipid profiles in the Isfahan population: an Isfahan cardiovascular disease risk factor survey, 1994. East Mediterr Health J 5:766–777Google Scholar
- 6.Foucan L, Kangambega P, Koumavi Ekouevi D, Rozet JE, Bangou-Brédent J (2000) Lipid profile in an adult population in Guadeloupe. Diabetes Metab 26:473–480Google Scholar
- 9.American Association of Clinical Endocrinologist (AACE) (2002) AACE lipid guidelines. Endocr Pract 6:4–52Google Scholar
- 10.Eghan BA Jr, Acheampong JW (2003) Dyslipidaemia in outpatients at General Hospital in Kumasi, Ghana: cross-sectional study. Croat Med J 44:576–578Google Scholar
- 11.National Cholesterol Education Program Expert Panel (2001) Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation and treatment of high cholesterol in adults (Adults Treatment Panel III). J Am Med Assoc 285:2486–2497CrossRefGoogle Scholar
- 12.Rifai N, Bachorik PS, Albers JJ (1999) Lipids, lipoproteins & apolipoproteins. In: Burtis CA, Ashwood ER (eds) Tietz textbook of clinical chemistry, 3rd edn. Saunders, Philadelphia, pp 809–861Google Scholar
- 13.World Health Organization (2010) Health systems financing: the path to universal coverage. The world health report 2010. World Health Organization, Geneva. http://www.who.int/whr/2010/en/index.html. Accessed 8 Sept 2010
- 14.Ministry of Health and Quality of Life, Republic of Mauritius (2009) The trends in diabetes and cardiovascular disease risk in Mauritius. Mauritius non communicable diseases survey reportGoogle Scholar
- 15.United States Preventive Services Task Force (2008) Screening for lipid disorders in adults: recommendation statement. http://www.uspreventiveservicestaskforce.org/uspstf08/lipid/lipidrs.htm. Accessed 8 Sept 2010
- 16.United States Preventive Services Task Force (2002) Screening for lipid disorders in adults: recommendations and rationale. Internet J Intern Med 3(2). http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijim/vol3n2/lipid.xml. Accessed 8 Sept 2010
- 19.Gupta R, Kaul V, Bhagat N, Agrawal M, Gupta VP, Misra A, Vikram NK (2008) Trends in prevalence of coronary risk factors in an urban Indian population: Jaipur Heart Watch-4. Indian Heart J 156:112–119Google Scholar
- 24.Centers for Disease Control. Heart Disease (On line). Available at http://www.cdc.gov/Features/WorldHeartDay/. Accessed 30 Sept 2010