Suppressive Effect of ERW on Lipid Peroxidation and Plasma Triglyceride Level

  • Masumi Abe
  • Shunpei Sato
  • Kazuko Toh
  • Takeki Hamasaki
  • Noboru Nakamichi
  • Kiichiro Teruya
  • Yoshinori Katakura
  • Shinkatsu Morisawa
  • Sanetaka Shirahata
Conference paper
Part of the Animal Cell Technology: Basic & Applied Aspects book series (ANICELLTECH, volume 16)

Abstract

Electrolyzed reduced water (ERW) containing hydrogen molecules and Pt nanoparticles is expected as a new antioxidant. Thiobarbituric acid reactive substances (TBARS) assay revealed that ERW had an inhibitory effect on the oxidation of low-density lipoproteins (LDL). In addition, ERW significantly suppressed LDL oxidation in the medium cultured J.774.A1 macrophage like cells. ERW inhibited Cu2+ ion-catalyzed oxidation of LDL ex vivo. ERW lowered lipid peroxide level in blood red cells and plasma triglyceride in rats fed a basal diet containing 2% cholesterol. These results suggest that ERW has anti-LDL oxidation and anti-hyperlipidemia effects.

Keywords

Electrolyzed reduced water Hyperlipidemia LDL Oxidation 

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Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Masumi Abe
    • 1
  • Shunpei Sato
    • 1
  • Kazuko Toh
    • 1
  • Takeki Hamasaki
    • 1
  • Noboru Nakamichi
    • 3
    • 4
  • Kiichiro Teruya
    • 5
    • 6
    • 7
  • Yoshinori Katakura
    • 2
    • 8
    • 9
  • Shinkatsu Morisawa
    • 10
  • Sanetaka Shirahata
    • 2
  1. 1.Department of Genetic Resources TechnologyKyushu UniversityFukuokaJapan
  2. 2.Faculty of AgricultureKyushu UniversityHigashi-kuJapan
  3. 3.Nihon Trim Co., Ltd.OsakaJapan
  4. 4.Functional Water Cell Analysis Center Co. Ltd.FukuokaJapan
  5. 5.Graduate School of Systems Life SciencesKyushu UniversityHigashi-kuJapan
  6. 6.Department of Genetic Resources Technology, Faculty of AgricultureKyushu UniversityFukuokaJapan
  7. 7.Graduate School of Bioresource and Bioenvironmental SciencesKyushu UniversityFukuokaJapan
  8. 8.Graduate School of System Life ScienceKyushu UniversityFukuokaJapan
  9. 9.Department of Genetic Resources TechnologyKyushu UniversityFukuokaJapan
  10. 10.Nihon Trim co. LTDOsakaJapan

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