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Regulation of Biological Control Agents pp 267–288Cite as

Proposals for Bacterial and Fungal Biocontrol Agents

Abstract

Registration of biological control agents containing micro-organisms is a long-lasting and costly procedure and has discouraged companies investing in the development of microbial biological control products. Risk assessment and regulation of microbial biological plant protection products is reviewed to develop proposals for an improvement of the current system. Minimum data requirements to be presented during pre-submission meeting were defined in order to support decisions on data requirements for the dossier and possible waivers. Criteria for the possible inclusion of microbial biocontrol agents into the “low risk products” list and support for the discussion of a comparative risk analysis are discussed. Major problems are the lack of validated risk assessment methods for microbials, knowledge gaps on the natural distribution of the biocontrol micro-organisms and on natural exposure of humans and other non-target organisms, and missing definitions allowing the identification of low risk products. Potential alternative approaches for the assessment of infectivity, toxicity, identification of relevant metabolites and the risk assessment procedures for metabolites and sensitisation are discussed. Proposals for waivers for potentially obsolete data requirements related to infectivity, effect on soil biota, fate and behaviour in the environment and genetic stability are recommended.

Keywords

  • Risk Assessment
  • Data Requirement
  • Trichoderma Harzianum
  • Intratracheal Instillation
  • Plant Protection Product

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Authors and Affiliations

  1. Department for Biotechnology and Biological Control, Institute for Phytopathology, Christian-Albrechts-University Kiel, 24118, Kiel, Germany

    Olaf Strauch & Ralf-Udo Ehlers

  2. Faculty of Biology, Institute of Microbiology University of Innsbruck, Innsbruck, A 6020, Austria

    Hermann Strasser

  3. GAB Consulting GmbH, 21769, Lamstedt, Germany

    Rüdiger Hauschild

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  1. Olaf Strauch
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  2. Hermann Strasser
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  3. Rüdiger Hauschild
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  4. Ralf-Udo Ehlers
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Correspondence to Olaf Strauch .

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  1. Institut für Phytopathologie, Abt. Biotechnologie und, Universität Kiel, Hermann-Rodewald-Str. 9, Kiel, 24118, Germany

    Ralf-Udo Ehlers

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Strauch, O., Strasser, H., Hauschild, R., Ehlers, RU. (2011). Proposals for Bacterial and Fungal Biocontrol Agents. In: Ehlers, RU. (eds) Regulation of Biological Control Agents. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3664-3_13

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