Proposal for Blood-Flow Imaging by Contrast Echo Using Counter-Crossed Beams
We propose a new contrast-echo method using counter-crossed beams of two ultrasonic frequencies as an ultrasound diagnostic for cancer. We call this the Counter-Cross Beam Contrast-Echo (C-CBCE) method. Sum and difference frequency components derived from nonlinear vibration of the contrast agents (microbubbles) driven by dual-frequency ultrasound are used in the C-CBCE method. In this study, we used Sonazoid microbubbles as we attempted to detect the sum frequency component generated by Sonazoid fixed in agar gel. We also measured the in-channel flow velocity of the Sonazoid.
KeywordsContrast-echo method Dual-frequency drive Contrast agents Nonlinear vibration Microbubbles Sum frequency component
This work was supported by KAKENHI (20300181).
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