Abstract
Sertoliform endometrioid carcinoma (SEC) of the ovary is an uncommon variant of endometrioid carcinoma of the ovary resembling sex cord-stromal tumor of pure Sertoli and Sertoli-Leydig cell type (SLCT). This entity was first described by Young et al. (1982). Since then only a few cases of this entity have been reported (Roth et al. 1982; Guerrieri et al. 1998; Remadi et al. 1995). SEC occurs in peri- and post menopausal women with an age range of 41–89 years (mean, 60 years). Abdominal enlargement secondary to a unilateral ovarian mass is the most common presentation. Up to 10% cases show bilaterality (Young et al. 1982). The patients very rarely present with androgenic symptoms such as virulization and, to date estrogenic manifestations have been reported in one case in a series of 13 cases (Young et al. 1982). Adequate sampling, a careful search for areas of conventional endometrioid carcinoma and immunohistochemical stains is helpful in the evaluation of SEC from true ovarian sex cord stromal tumors. It is important to recognize this variant of endometrioid carcinoma and especially differentiate it from a sex cord stromal tumor. SEC as it behaves, is a low grade malignancy and displays a good prognosis if confined to the ovary.
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Sur, M., Daya, D. (2010). Sertoliform Endometrioid Carcinoma of the Ovary: Diagnosis and Prognosis. In: Hayat, M. (eds) Methods of Cancer Diagnosis, Therapy, and Prognosis. Methods of Cancer Diagnosis, Therapy and Prognosis, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-2918-8_5
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