The Ethics of Synthetic Biology: Outlining the Agenda
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The projects and aims of synthetic biology raise various ethical questions, challenging some of our basic moral concepts. This chapter addresses these issues in three steps. First, we present an overview of different types of ethical issues related to synthetic biology by assigning them to three main categories: method-related, application-related, and distribution-related issues. The first category concerns the procedure and aims of synthetic biology, the second deals with certain planned applications of synthetic biology and the third with questions of distribution and access to procedures and products of this technology. Next, we address a statement often raised in the discussion about ethics of synthetic biology, namely that the ethical issues of synthetic biology have been discussed in previous debates and therefore do not need to be addressed again. We argue that past debates do not render the discussion of ethical issues superfluous because synthetic biology sets these issues in a new context and because the discussion of such issues fulfills in itself an important function, namely by stimulating thought about our relationship to technology and nature. Furthermore, given that synthetic biology’s aims go beyond those of previous technologies, we suggest that it does in fact raise novel ethical issues. Finally, we present opinions of European synthetic biologists on ethical issues in their field. At such an early stage of technological development, synthetic biologists play an important role in the assessment of their discipline, and are best placed to estimate the scientific potential of the field. In an attempt to capture the intuitions of the European synthetic biology community, we have carried out interviews, the results of which we briefly summarize in this last section. By presenting an overview of the various ethical issues and their actual and perceived importance, this chapter aims at providing a first outline for the agenda for an ethics of synthetic biology.
KeywordsEthical Issue Moral Judgment Synthetic Biology Somatic Cell Nuclear Transfer Ethical Question
- Daniels N (2008) Reflective Equilibrium. In: Zalta EN (ed.) The Standford Encyclopedia of Philosophy (Fall 2008 Edition). http://plato.stanford.edu/archives/fall2008/entries/reflective-equilibrium/. Accessed 21 December, 2008
- Deplazes A (2009) Piecing together a puzzle: An exposition of synthetic biology. EMBO reports 10: 428–432.Google Scholar
- ETC (2007) Extreme Genetic Engineering an Introduction to Synthetic Biology. http://www.etcgroup.org/upload/publication/602/01/synbioreportweb.pdf. Accessed 21 December, 2008
- Ganguli-Mitra A, Schmidt M, Torgersen H, Deplazes A, Biller-Andorno N (2009) of Newtons and heretics. Nature Biotechnology 27(4): 321–2.Google Scholar
- Garfinkel MS, Endy D, Epstein GL, Friedman RM (2007) Synthetic Genomics, Options for Governance. http://www.jcvi.org/cms/fileadmin/site/research/projects/synthetic-genomics-report/synthetic-genomics-report.pdf. Accessed 21 December, 2008.
- Gold ER (2002) Merging Business and Ethics: New Models for Using Biotechnological Intellectual Property. In: Ruse M, Castle D (eds.) Genetically Modified Foods: Debating Biotechnology. Prometheus Books, New YorkGoogle Scholar
- NEST (2005) Reference Document on Synthetic Biology 2005/2006 Pathfinder Initiatives http://ftp://ftp.cordis.europa.eu/pub/nest/docs/syntheticbiology2004.pdf Accessed 21 December, 2008
- OECD (2001) Understanding the Digital Divide. http://www.oecd.org/dataoecd/38/57/1888451.pdf. Accessed 21 December, 2008
- Royal Society (2004) Social and Ethical Issues. In: Nanoscience and Nanotechnologies: Opportunities and Uncertainties. http://www.nanotec.org.uk/finalReport.htm. Accessed 21 December, 2008
- Schmidt M, Torgersen H, Ganguli-Mitra A, Kelle A, Deplazes A, Biller-Andorno N (2008) SYNBIOSAFE e-conference: Online community discussion on the societal aspects of synthetic biology. Systems and Synthetic BiologyGoogle Scholar
- Weiss R (2007) Synthetic Biology: From Bacteria to Stem Cells. In: Annual ACM IEEE Design Automation Conference: Proceedings of the 44th annual conference on Design Automation. http://doi.acm.org/10.1145/1278480.1278640. Accessed 21 December, 2008
- Wilson J (2001) Biotechnology Intellectual Property – Bioethical Issues. In: Encyclopedia of Life Science. John Wiley & Sons, Ltd. http://www.els.net. Accessed 21 December, 2008