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The Epigenomics of Cancer

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An Omics Perspective on Cancer Research

Abstract

Epigenomics is the genome-wide study of epigenetics such as DNA methylation and histone modification. Epigenetic abnormality plays an important role in the pathogenesis of most cancers. Among these modifications, DNA methylation is the best-known and most important because of its heritable character. Here, recent advances in several technologies for genome-wide profiling of DNA methylation are reviewed.

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Authors and Affiliations

  1. Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, 371-8511, Japan

    Izuho Hatada

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  1. Izuho Hatada
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Correspondence to Izuho Hatada .

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Editors and Affiliations

  1. Dept. Clinical Oncology, Queen Elizabeth Hospital, Gascoigne Road 30, Kowloon, Hong Kong/PR China

    William C.S. Cho

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Hatada, I. (2010). The Epigenomics of Cancer. In: Cho, W. (eds) An Omics Perspective on Cancer Research. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-2675-0_4

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