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Molecular Methods for Identification of Aspergillus Species

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Aspergillosis: From Diagnosis to Prevention

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Abstract

Using molecular methods for Aspergillus species identification can be a cost-effective, rapid, discriminatory, and objective approach for delineating Aspergillus species in a clinical microbiology laboratory. Identification of Aspergillus to species level is important for therapeutic decision-making, since different species have variable susceptibilities to available antifungal drugs. Standardization of loci and methods, availability of appropriate guidelines for species definitions using sequence information, and robust sequence databases will make these technologies more conducive to use in a clinical microbiology laboratory. This book section focuses on utilization of molecular methods, specifically comparative sequence identification methods, for the identification of Aspergillus at the species level.

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Authors and Affiliations

  1. Mycotic Diseases Branch, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA

    Eszter Deak & S. Arunmozhi Balajee

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Correspondence to S. Arunmozhi Balajee .

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  1. Porto Alegre, Complexo Hospitalar Santa Casa de, Av. Independencia 155, Porto Alegre, 90035-075, Brazil

    Alessandro Comarú Pasqualotto

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Deak, E., Balajee, S.A. (2009). Molecular Methods for Identification of Aspergillus Species. In: Comarú Pasqualotto, A. (eds) Aspergillosis: From Diagnosis to Prevention. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-2408-4_5

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