Skip to main content
SpringerLink
Log in

Heeft wetenschappelijk onderzoek op het terrein van de kinder- en jeugdpsychiatrie opgeleverd wat we verwacht hadden?

  • Chapter
  • First Online:
Transformaties in de jeugdzorg

  • 771 Accesses

Samenvatting

In de somatische gezondheidszorg, vooral in de preventieve gezondheidszorg, heeft empirisch wetenschappelijk onderzoek bijgedragen aan het vergroten van de gezondheid. De vraag is of dit ook geldt voor de kinder- en jeugdpsychiatrie. Lange tijd speelde wetenschappelijk onderzoek in de kinder- en jeugdpsychiatrie immers geen rol, enkele uitzonderingen daargelaten. Dit artikel geeft een selectief overzicht over de rol van wetenschappelijk onderzoek in de kinder- en jeugdpsychiatrie. Dit vak heeft de afgelopen decennia weer aansluiting gevonden bij andere medische disciplines. Hierin heeft wetenschappelijk onderzoek een belangrijke rol gespeeld. Toch heeft wetenschappelijk onderzoek maar weinig bijgedragen aan verbetering van preventie en interventie van psychiatrische stoornissen bij kinderen en adolescenten. Blijkbaar is de etiologische en fenotypische heterogeniteit zo complex dat de toepassing van nieuwe technieken, zoals de genetica en (neuro)imaging, binnen de kinder- en jeugdpsychiatrie niet tot de grote successen heeft geleid die in de algemene geneeskunde plaatsvonden.

Abstract

In somatic healthcare, preventive healthcare in particular, empirical scientific research has helped improve health. The question is whether this also applies to psychiatry for children and adolescents. After all, there was a lengthy period during which scientific research played no part in child and adolescent psychiatry (with just a few exceptions). This article gives a selective overview of the role of scientific research in child and adolescent psychiatry. Over recent decades, this field has once again found its place in amongst other medical disciplines. Scientific research has played a key role in this. Nevertheless, scientific research has contributed little to improvements in prevention and interventions for psychiatric disorders in children and adolescents. It would seem that the aetiological and phenotypic heterogeneity is so complex that applying new techniques such as genetics, imaging and neuro-imaging has not led to the major successes in child and adolescent psychiatry that have been achieved in medicine in general.

Frank C. Verhulst MD, PhD is hoogleraar kinder- en jeugdpsychiatrie en afdelingshoofd van de afdeling Kinder- en Jeugdpsychiatrie/psychologie van het ErasmusMC te Rotterdam.

Deze bijdrage is grotendeels ook gepubliceerd in: Veertig Jaar Kinder- en Jeugdpsychiatrie: Terugblikken en Vooruitzien. Liber Amicorum voor Fop Verheij. Assen: Van Gorcum, 2014.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 19.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 27.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatuur

  • Achenbach, T. M. (1966). The classification of children’s psychiatric symptoms: A factor-analytic study. Psychological Monographs, 80(615), 1–37. doi:10.1037/h0093906, 5968338.

    Article  PubMed  Google Scholar 

  • Achenbach, T. M. (1974). Developmental psychopathology (2nd ed.). New York: Ronald Press, Wiley.

    Google Scholar 

  • Achenbach, T. M. (1978). The Child Behavior Profile: I. Boys aged 6–11. Journal of Consulting and Clinical Psychology, 46, 478–488. doi:10.1037/0022-006X.46.3.478, 670491.

    Article  PubMed  Google Scholar 

  • Achenbach, T. M. (2009). The Achenbach system of empirically based assessment (ASEBA): Development, findings, theory, and applications. Burlington: University of Vermont, Research Center for Children, Youth, & Families.

    Google Scholar 

  • Achenbach, T. M., & Rescorla, L. A. (2007). Multicultural understanding of child and adolescent psychopathology: Implications for mental health assessment. New York: The Guilford Press.

    Google Scholar 

  • Achenbach, T. M., McConaughy, S. H., & Howell, C. T. (1987). Child/adolescent behavioral and emotional problems: Implications of cross-informant correlations for situational specificity. Psychological Bulletin, 101, 213–232. doi:10.1037/0033-2909.101.2.213, 3562706.

    Article  PubMed  Google Scholar 

  • Achenbach, T. M., Becker, B., Döpfner, M., Heiervang, E., Roessner, V., Steinhausen, H., et al. (2008). Multicultural assessment of child and adolescent psychopathology with ASEBA and SDQ instruments: Research findings, applications, and future directions. Journal of Child Psychology and Psychiatry and Allied Disciplines, 49, 251–275. doi:10.1111/j.1469-7610.2007.01867.x.

    Article  Google Scholar 

  • Achenbach, T. M., McConaughy, S. H., Ivanova, M. Y., & Rescorla, L. A. (2012). Manual for the ASEBA Brief Problem Monitor™(BPM). Burlington: University of Vermont, Research Center for Children, Youth, & Families.

    Google Scholar 

  • Althaus, M. (2000). Visual attention and autonomic adaptivity to attention-demanding tasks in children with autistic-type behavioral problems. Groningen: Rijksuniversiteit Groningen, Academisch Proefschrift.

    Google Scholar 

  • American Psychiatric Association (1980). Diagnostic and statistical manual of mental disorders (3rd ed.) (DSM-III). Washington, DC: Author.

    Google Scholar 

  • Andreasen, N. C. (2001). Brave new brain. Oxford: Oxford University Press.

    Google Scholar 

  • Angold, A., & Fisher, P. W. (1999). Interviewer based interviews. In D. Shaffer, C. P. Lucas, & E. Richters (eds.), Diagnostic Assessment in Child and Adolescent Psychopathology (pp. 34–36). New York: The Guildford Press.

    Google Scholar 

  • Buitelaar, J. K. (1991). Psychopharmacology of autism: Clinical and ethological studies on the behavioural effects of a synthetic adrenocorticotrophic hormone (4–9) analog. Utrecht: Rijksuniversiteit Utrecht, Academisch proefschrift.

    Google Scholar 

  • Cantwell, D. P. (1988). DSM-III studies. In M. Rutter, A. Hussain Tuma, & I. S. Lann (eds.), Assessment and diagnosis in child psychopathology (pp. 3–35). London: David Fulton Publishers.

    Google Scholar 

  • Caspi, A., McClay, J., Moffitt, T. E., Mill, J., Martin, J., Craig, I. W., et al. (2002). Role of genotype in the cycle of violence in maltreated children. Science, 297, 851–854. doi:10.1126/science,1072290, 12161658.

    Article  PubMed  Google Scholar 

  • Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., et al. (2003). Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. Science, 301(5631), 386–389. doi:10.1126/science,1083968, 12869766.

    Article  PubMed  Google Scholar 

  • Coghill, D., & Sonuga-Barke, E. (2012). Annual research review: Categories versus dimensions in the classification and conceptualisation of child and adolescent mental disorders – implications of recent empirical study. Journal of Child Psychology and Psychiatry, 53, 469–489. doi:10.1111/j.1469-7610.2011.02511.x, 22288576.

    Article  PubMed  Google Scholar 

  • Conners, C. K., & Eisenberg, L. (1963). The effects of methylphenidate on symptomatology and learning in disturbed children. American Journal of Psychiatry, 120, 459–466. doi:10.1176/ajp.120.5.458.

    Article  Google Scholar 

  • Conners, C. K., Eisenberg, L., & Barcai, A. (1967). Effect of dextroamphetamine on children: Studies on subjects with learning disabilities and school behaviour problems. Archives of General Psychiatry, 17, 478–485. doi:10.1001/archpsyc.1967.01730280094011, 4861380.

    Article  PubMed  Google Scholar 

  • Crone, E. (2008). Het puberende brein. Amsterdam: Bert Bakker.

    Google Scholar 

  • Davey Smith, G. (2011). Epidemiology, epigenetics and the ‘Gloomy Prospect’: Embracing randomness in population health research and practice. International Journal of Epidemiology, 40, 537–562. doi:10.1093/ije/dyr117.

    Article  Google Scholar 

  • Duncan, L. E. (2013). Paying attention to all results, positive and negative. Journal of the American Journal of Child and Adolescent Psychiatry, 52, 462–465. doi:10.1016/j.jaac.2013.02.007.

    Article  Google Scholar 

  • Engeland, H. van. (1980). Over ontwikkelingspsychosen: Een psychofysiologisch onderzoek naar input-modulatiestoornissen. Utrecht: Academisch Proefschrift.

    Google Scholar 

  • Ferdinand, R. F. (1995). Psychopathology in adolescents and young adults. Rotterdam: Erasmus Universiteit, Academisch proefschrift.

    Google Scholar 

  • Fergusson, D. M. (1995). A brief introduction to structural equation models. In F. C. Verhulst, & H. M. Koot (eds.), The epidemiology of child and adolescent psychopathology (pp. 122–145). Oxford: Oxford University Press.

    Google Scholar 

  • Fox, J. P., Hall, C. E., & Elveback, L. R. (1970). Epidemiology: Man and disease (pp. 19–30). London: The MacMillan Company.

    Google Scholar 

  • Fraiberg, S. H. (1959). The magic years. New York: Charles Scribner’s Sons.

    Google Scholar 

  • Galton, F. (1876). The history of twins as a criterion of the relative powers of nature and nurture. Royal Anthropological Institute of Great Britain and Ireland Journal, 6, 391–406. doi:10.2307/2840900.

    Article  Google Scholar 

  • Gunning, B. (1992). A controlled trial of clonidine in hyperkinetic children. Rotterdam: Erasmus Universiteit, Academisch proefschrift.

    Google Scholar 

  • Heijmens Visser, J. (2002). Long-term outcome of psychopathology in childhood and adolescence: A clinical epidemiological study. Rotterdam: Erasmus Universiteit, Academisch proefschrift.

    Google Scholar 

  • Hofstra, M. B. (2000). Psychopathology from childhood into adulthood: Follow-up of an epidemiological sample. Rotterdam: Erasmus Universiteit, Academisch proefschrift.

    Google Scholar 

  • Hudziak, J. J., & Novins, D. K. (2013). Illuminating the complexities of developmental psychopathology: Special series on longitudinal and birth cohort studies. Journal of the American Academy of Child and Adolescent Psychiatry, 52, 6–8. doi:10.1016/j.jaac.2012.10.016, 23265628.

    Article  PubMed  Google Scholar 

  • International Human Genome Sequencing Consortium (IHGSC). (2004). Finishing the euchromatic sequence of the human genome. Nature, 431, 931–945. doi:10.1038/nature03001.

    Article  Google Scholar 

  • Koot, H. M., Crijnen, A. A. M., & Ferdinand, R. F. (1999). Child psychiatric epidemiology: Accomplishments and future directions. Assen: Van Gorcum.

    Google Scholar 

  • Mackenbach, J. P. (2011). Successen van preventie 1970–2010. Rotterdam: ErasmusMC, afdeling Maatschappelijke Gezondheidszorg.

    Google Scholar 

  • McGuffin, P., & Martin, N. (1999). Science, medicine, and the future. Behaviour and genes. British Medical Journal, 319(7201), 37–40. doi:10.1136/bmj.319.7201.37, 1116141, 10390460.

    Article  PubMed  PubMed Central  Google Scholar 

  • Meaney, M. J. (2001). Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Annual Review Neuroscience, 24, 1161–1192. doi:10.1146/annurev.neuro.24.1.1161.

    Article  Google Scholar 

  • Meurs, I. van. (2009). Intergenerational transmission of child problem behavior. Rotterdam: Erasmus Universiteit, Academisch proefschrift.

    Google Scholar 

  • Minderaa, R. B. (1985). Neurochemical aspects of childhood autism. Rotterdam: Erasmus Universiteit, Academisch proefschrift.

    Google Scholar 

  • Molina, B. S., Hinshaw, S. P., Swanson, J. M., Arnold, L. E., Vitiello, B., Jensen, P. S., et al. (2009). The MTA at 8 years: Prospective follow-up of children treated for combined-type ADHD in a multisite study. Journal of the American Academy of Child and Adolescent Psychiatry, 48, 484–500. doi:10.1097/CHI.0b013e31819c23d0, 3063150, 19318991.

    Article  PubMed  PubMed Central  Google Scholar 

  • Oord, E. J. van den, Verhulst, F. C., & Boomsma, D. I. (1996). A genetic study of maternal and paternal ratings of problem behaviors in 3-year-old twins. Journal of Abnormal Psychology, 105, 349–357.

    Google Scholar 

  • Oosterlaan, J., Logan, G. D., & Sergeant, J. A. (1998). Response inhibition in AD/HD, CD, comorbid AD/HD + CD, anxious, and control children: A meta-analysis of studies with the stop task. Journal of Child Psychology and Psychiatry, 39, 411–425. doi:10.1017/S0021963097002072, 9670096.

    Article  PubMed  Google Scholar 

  • Plomin, R., & Daniels, D. (1987). Why are children in the same family so different from one another? Behavioral and Brain Sciences, 10, 1–16. doi:10.1017/S0140525X00055941.

    Article  Google Scholar 

  • Plomin, R., DeFries, J. C., & McClearn, G. E. (1980). Behavioral genetics: A primer. San Francisco: W.H. Freema.

    Google Scholar 

  • Plomin, R., DeFries, J. C., & McGuffin, P. (2003). Behavioral genetics in the postgenomic era. Washington: American Psychological Association. doi:10.1037/10480-000.

    Book  Google Scholar 

  • Reef, J. (2010). Adult consequences of child psychopathology. Rotterdam: Erasmus Universiteit, Academisch proefschrift.

    Google Scholar 

  • Remschmidt, H. (1996). Changing views: New perspectives in child psychiatric research. European Child and Adolescent Psychiatry, 5, 2–10. 9117535.

    PubMed  Google Scholar 

  • Robins, L. N. (1974) Deviant children grown up: A sociological and psychiatric study of sociopathic personality. New York: Krieger.

    Google Scholar 

  • Roza, S. J. (2008). Prenatal and early postnatal brain development. Rotterdam: Erasmus Universiteit, Academisch proefschrift.

    Google Scholar 

  • Rutter, M. (2006). Genes and behavior: Nature-nurture interplay explained. Malden: Blackwell Publishing.

    Google Scholar 

  • Rutter, M., Tizard, J., & Whitmore, K. (1970). Education, health and behaviour. London: Longmans.

    Google Scholar 

  • Rutter, M., Taylor, E., & Hersov, L. (1994). Child and Adolescent Psychiatry: Modern approaches. London: Blackwell Scientific Publications.

    Google Scholar 

  • Silva, P. A., & Stanton, W. R. (1996). Child to Adult: The Dunedin Multidisciplinary Health and Development Study. Oxford: Oxford University Press.

    Google Scholar 

  • Stringaris, A. (2012). Predicting treatment outcomes: Encouraging findings from neuroimaging. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 1228.

    Google Scholar 

  • Swaab, D. (2010). Wij zijn ons brein: Van baarmoeder tot Alzheimer. Amsterdam: Uitgeverij Contact.

    Google Scholar 

  • Szatmari, P., Charman, T., & Constantino, J. N. (2012). Into, and out of, the “Valley of Death”: Research in autism spectrum disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 1108–1112. doi:10.1016/j.jaac.2012.08.027, 23101736.

    Article  PubMed  Google Scholar 

  • Thapar, A., & Rutter, M. (2009). Do prenatal risk factors cause psychiatric disorder? Be wary of causal claims. British Journal of Psychiatry, 195, 100–101. doi:10.1192/bjp.bp.109.062828, 19648537.

    Article  PubMed  Google Scholar 

  • Tiemeier, H., Velders, F. P., Szekely, E., Roza, S. J., Dieleman, G., Jaddoe, V. W., et al. (2012). The Generation R Study: A review of design, findings to date, and a study of the 5-HTTLPR by environmental interaction from fetal life onward. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 1119–1135. doi:10.1016/j.jaac.2012.08.021, 23101739.

    Article  PubMed  Google Scholar 

  • Uher, R., & Rutter, M. (2012). Basing psychiatric classification on scientific foundation: Problems and prospects. International Review of Psychiatry, 24, 591–605. doi:10.3109/09540261.2012.721346, 23244614.

    Article  PubMed  Google Scholar 

  • Valk, J.C. van der, Verhulst, F. C., Stroet, T. M., & Boomsma, D. I. (1998). Quantitative genetic analysis of internalising and externalising problems in a large sample of 3-year-old twins. Twin Research, 1, 25–33.

    Google Scholar 

  • Verhulst, F. C. (1985) Mental Health in Dutch Children. Rotterdam: Erasmus Universiteit, Academisch proefschrift.

    Google Scholar 

  • Verhulst, F. C., & Koot, H. M. (1992). Child psychiatric epidemiology: Concepts, methods and findings. Newbury park: sage Publications. doi:10.4135/9781483325804.

    Book  Google Scholar 

  • Verhulst, F. C., Ende, J. van der, Ferdinand, R. F., & Kasius, M. C. (1997). The prevalence of DSM-III-R diagnoses in a national sample of Dutch adolescents. Archives of General Psychiatry, 54, 329–336.

    Google Scholar 

  • Verhulst, F. C., Donker, A. G., & Hofstra, M. B. (2001). De ontwikkeling van antisociaal gedrag. In R. Loeber, N. W. Slot, & J. A. Sergeant (red.), Ernstige en gewelddadige jeugddelinquentie (pp. 155–170). Houten: Bohn Stafleu van Loghum.

    Google Scholar 

  • Vitaro, F., & Tremblay, R. E. (2008). Clarifying and maximizing the usefulness of targeted preventive interventions. In M. Rutter, D. V. M. Bishop, D. S. Pine, S. Scott, J. Stevenson, E. Taylor, & A. Thapar (eds.), Rutter’s Child and Adolescent Psychiatry (pp. 145–159). Malden: Blackwell Publishing.

    Google Scholar 

  • Weisz, J. R., & Gray, J. S. (2008). Evidence –based psychotherapy for children and adolescents: Data from the present and a model for the future. Child and Adolescent Mental Health, 13, 54–66. doi:10.1111/j.1475-3588.2007.00475.x.

    Article  Google Scholar 

  • Weisz, J. R., Ugueto, A. M., Cheron, D. M., & Herren, J. (2013). Evidence-based youth psychotherapy in the mental health ecosystem. Journal of Clinical Child and Adolescent Psychology, 42, 274–286. doi:10.1080/15374416.2013.764824, 23402704.

    Article  PubMed  Google Scholar 

  • Wielemaker, J. F. (2009). Langdurig klinisch behandeld in de kinder- en jeugdpsychiatrie; een follow-up onderzoek na 5 tot 25 jaar. Rotterdam: Erasmus Universiteit, Academisch proefschrift.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Rotterdam, The Netherlands

    Frank C. Verhulst

Authors
  1. Frank C. Verhulst
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Afdeling Ontwikkelingspsychologie, Vrije Universiteit Afdeling Ontwikkelingspsychologie, Amsterdam, The Netherlands

    Sander Begeer

  2. Hogeschool van Amsterdam , Gouda, The Netherlands

    Leonieke Boendermaker

  3. KU Leuven , Leuven, Belgium

    Hilde Colpin

  4. Abcoude, Noord-Holland, The Netherlands

    Marca Geeraets

  5. Afd. Pedagogiek, Onderwijskunde, Universiteit van Amsterdam Afd. Pedagogiek, Onderwijskunde, Amsterdam, The Netherlands

    Helma Koomen

  6. Department of Psychiatry, Radboud UMC Department of Psychiatry, Nijmegen, The Netherlands

    Nanda Lambregts-Rommelse

  7. KU Leuven , Aalter, Belgium

    Karla Van Leeuwen

  8. AMC/ De Bascule , Amsterdam, The Netherlands

    Ramon Lindauer

  9. Universiteit van Amsterdam , Amsterdam, The Netherlands

    Geertjan Overbeek

  10. Jonkershove, Belgium

    Peter Prinzie

  11. Ermelo, The Netherlands

    Gerda Smid

  12. Department of Developmental Personality, Universiteit Gent Department of Developmental Personality, Gent, Belgium

    Bart Soenens

  13. Algemene Sociale Wetenschappen, Universiteit Utrecht Algemene Sociale Wetenschappen, Zeist, The Netherlands

    Gonneke Stevens

Copyright information

© 2016 Bohn Stafleu van Loghum

About this chapter

Cite this chapter

Verhulst, F.C. (2016). Heeft wetenschappelijk onderzoek op het terrein van de kinder- en jeugdpsychiatrie opgeleverd wat we verwacht hadden?. In: Begeer, S., et al. Transformaties in de jeugdzorg. Bohn Stafleu van Loghum, Houten. https://doi.org/10.1007/978-90-368-1495-9_1

Download citation

  • DOI: https://doi.org/10.1007/978-90-368-1495-9_1

  • Published:

  • Publisher Name: Bohn Stafleu van Loghum, Houten

  • Print ISBN: 978-90-368-1494-2

  • Online ISBN: 978-90-368-1495-9

  • eBook Packages: Dutch language eBook collection

Publish with us

Policies and ethics

Search

Navigation